# Health-promoting lifestyle as a predictor of well-being in Honduran university students: a structural equation modeling approach with mental health and sleep quality as mediators

**Authors:** Marcio Alexander Castillo-Díaz, Carlos Alberto Henao Periañez

PMC · DOI: 10.3389/fpsyg.2025.1735602 · Frontiers in Psychology · 2026-01-20

## TL;DR

This study shows that a health-promoting lifestyle improves well-being in Honduran university students, mainly through better sleep and reduced depression.

## Contribution

The study introduces an integrative model linking health-promoting lifestyles to well-being via mental health and sleep quality in a Latin American context.

## Key findings

- A health-promoting lifestyle directly and indirectly improves subjective well-being.
- Depression and sleep quality mediate the relationship between lifestyle and well-being.
- Anxiety does not significantly mediate this relationship.

## Abstract

Although a health-promoting lifestyle is associated with greater well-being among university students, the psychological (anxiety, depression) and physiological (sleep quality) mechanisms underlying this relationship remain insufficiently established, highlighting the need for integrative models that better explain well-being. Moreover, empirical evidence on these relationships is still limited in lower–middle-income countries. Accordingly, this study tested a model in which a health-promoting lifestyle predicts subjective well-being, with depression, anxiety, and sleep quality serving as mediating variables within a Latin American context.

A cross-sectional design was employed with a sample of 6,704 Honduran university students. The instruments included a short version of the Health-Promoting Lifestyle Profile II (HPLP-II), the Patient Health Questionnaire-9 (PHQ-9), the Generalized Anxiety Disorder 7-item Scale (GAD-7), the Single-Item Sleep Quality Scale (SQS), and the World Health Organization Well-Being Index (WHO-5). Measurement models for each instrument and a multiple-mediation structural equation model were estimated.

The final structural model demonstrated adequate fit and explained 61.6% of the variance in well-being. A health-promoting lifestyle predicted greater well-being both directly and indirectly. Among the mediators, depression and sleep quality showed significant indirect effects, whereas anxiety did not play a statistically significant mediating role. Overall, the findings confirm that a health-promoting lifestyle is associated with lower depressive symptomatology and better sleep quality, which in turn enhances subjective well-being.

The findings support an integrative model in which a health-promoting lifestyle explains student well-being, highlighting depression and sleep quality as key pathways of influence. These results broaden the understanding of well-being from a multidimensional perspective and provide actionable evidence for designing institutional policies and intervention strategies that promote healthy lifestyle behaviors and well-being, particularly in Latin American settings.

## Linked entities

- **Diseases:** depression (MONDO:0002050), anxiety (MONDO:0005618)

## Full-text entities

- **Diseases:** anxiety (MESH:D001007), Generalized Anxiety Disorder (MESH:C000726808), depression (MESH:D003866)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

62 references — full list in the complete paper: https://tomesphere.com/paper/PMC12864460/full.md

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Source: https://tomesphere.com/paper/PMC12864460