# Acute Exacerbation of Chronic Periapical Pathology in a Dentist: An Autobiographical Case Report

**Authors:** Ramya Sekar, Thangadurai Maheswaran, Mathimaraiselvan Chittrarasu, Sethuraman Vijayparthiban, Ramamurthy Suresh

PMC · DOI: 10.7759/cureus.100715 · Cureus · 2026-01-03

## TL;DR

A dentist's personal experience with a tooth infection highlights the importance of timely dental treatment and careful pain management.

## Contribution

This case report explores analgesic rotation and symptom-driven pain management in acute dental exacerbations.

## Key findings

- Endodontic intervention provided immediate pain relief in a dentist with a chronic periapical granuloma.
- Analgesic rotation and de-escalation were used to manage pain while minimizing toxicity.
- Timely treatment remains critical for acute periapical abscesses despite analgesic strategies.

## Abstract

Acute exacerbations of chronic periapical pathology require prompt surgical or endodontic intervention, supported by pharmacotherapy. The role of analgesic selection, escalation, and rotation in acute dental pain remains underexplored. A 39-year-old male dentist with a 27-year history of trauma to the lower left central incisor presented with acute pain of three hours’ duration. The tooth was non-vital with a stable periapical granuloma documented for over 15 years. Self-medication began with paracetamol, escalating to ibuprofen, aceclofenac, and etoricoxib, when pain worsened. Amoxicillin and metronidazole were also taken for infection control. On day three, endodontic access without anesthesia yielded minimal pus drainage but immediate pain relief. The canal was initially left open, then medicated with calcium hydroxide, and finally obturated with gutta-percha and zinc oxide-eugenol sealer. Three years of follow-up showed no recurrence. This case demonstrates symptom-driven analgesic escalation and de-escalation in an informed patient and raises the concept of analgesic rotation for reducing cumulative toxicity. While this may be relevant in chronic pain management, its role in acute odontogenic pain is limited, especially for agents with shared adverse profiles such as non-steroidal anti-inflammatory drugs (NSAIDs). Timely endodontic intervention remains the cornerstone of treatment for acute periapical abscesses. Analgesic prescribing should be individualized and symptom-based rather than fixed-duration, with rotation considered selectively.

## Linked entities

- **Chemicals:** paracetamol (PubChem CID 1983), ibuprofen (PubChem CID 3672), aceclofenac (PubChem CID 71771), etoricoxib (PubChem CID 123619), amoxicillin (PubChem CID 33613), metronidazole (PubChem CID 4173), calcium hydroxide (PubChem CID 6093208)
- **Diseases:** periapical granuloma (MONDO:0006897)

## Full-text entities

- **Diseases:** dental pain (MESH:D010146), trauma (MESH:D014947), acute pain (MESH:D059787), toxicity (MESH:D064420), Periapical Pathology (MESH:D010483), chronic pain (MESH:D059350), periapical granuloma (MESH:D010484), periapical abscesses (MESH:D010482), infection (MESH:D007239)
- **Chemicals:** etoricoxib (MESH:D000077613), calcium hydroxide (MESH:D002126), paracetamol (MESH:D000082), ibuprofen (MESH:D007052), zinc oxide (MESH:D015034), aceclofenac (MESH:C056498), eugenol (MESH:D005054), metronidazole (MESH:D008795), Amoxicillin (MESH:D000658)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12864158/full.md

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Source: https://tomesphere.com/paper/PMC12864158