# Co-occurrence of Vogt–Koyanagi–Harada disease, diabetic retinopathy, and advanced chronic kidney disease: a case report

## TL;DR

A 53-year-old man with chronic kidney disease and diabetes was diagnosed with Vogt–Koyanagi–Harada disease, highlighting the diagnostic challenges and treatment complexities in patients with multiple health issues.

## Contribution

The novelty lies in presenting a rare co-occurrence of VKH disease with diabetic retinopathy and chronic kidney disease, emphasizing unique diagnostic and treatment challenges.

## Key findings

- VKH diagnosis was confirmed despite the absence of typical anterior chamber inflammation.
- Treatment with corticosteroids and adalimumab showed a positive response.
- The case highlights the need for careful management of corticosteroids in patients with diabetes and renal failure.

## Abstract

This study aimed to report a case of Vogt–Koyanagi–Harada (VKH) disease in a 53-year-old man with renal failure and diabetes, highlighting the challenges in diagnosing VKH amidst complex systemic comorbidities.

A case report was conducted through a retrospective review of the patient’s medical history, clinical presentations, diagnostic workup, and treatment course.

A 53-year-old man with renal failure, hypoalbuminemia, and diabetes presented with blurred vision. Initial findings included bilateral serous retinal detachment with subretinal septa, choroidal thickening, and left eye vitreous hemorrhage, without anterior chamber inflammation. Subsequent anterior segment inflammation and a positive response to combined corticosteroids and adalimumab confirmed VKH.

This case underscores the diagnostic complexity of VKH in patients with multiple systemic conditions. Corticosteroid management in such individuals requires meticulous attention, emphasizing the need for close monitoring of blood glucose and overall systemic status during treatment.