# Sixteen-Year Interval CT Comparison in Chiari II Malformation After Early Ventriculoperitoneal Shunting: Marked Ventricular Improvement and a Prolonged Seizure-Free Interval

**Authors:** Ahmed H Khird, Alaa A Alotaibi

PMC · DOI: 10.7759/cureus.102802 · Cureus · 2026-02-01

## TL;DR

A girl with Chiari II malformation and a VP shunt showed significant brain ventricle improvement and remained seizure-free for 16 years.

## Contribution

Demonstrates long-term clinical improvement in a patient with severe congenital brain anomalies and VP shunting.

## Key findings

- Marked ventricular improvement was observed over a 16-year period.
- The patient remained seizure-free for an extended duration despite severe supratentorial malformations.

## Abstract

Chiari II malformation is commonly associated with hydrocephalus requiring early cerebrospinal fluid (CSF) diversion and may coexist with complex supratentorial developmental abnormalities. As a result, patients with severe congenital structural brain anomalies and long-term ventriculoperitoneal (VP) shunting often experience neurodevelopmental impairment and are at increased risk of epilepsy. We report a 17-year-old girl with Chiari II malformation, repaired myelomeningocele, and ventriculoperitoneal shunting since birth (revision at five years of age), demonstrating marked ventricular improvement over a 16-year interval and a prolonged seizure-free interval despite severe congenital supratentorial malformations.

## Linked entities

- **Diseases:** hydrocephalus (MONDO:0001150), epilepsy (MONDO:0005027), myelomeningocele (MONDO:0017069)

## Full-text entities

- **Diseases:** neurodevelopmental impairment (MESH:D009422), developmental abnormalities (MESH:D006130), Seizure (MESH:D012640), hydrocephalus (MESH:D006849), epilepsy (MESH:D004827), myelomeningocele (MESH:D008591), brain anomalies (MESH:D001927), supratentorial malformations (MESH:D015173), Chiari II Malformation (MESH:D001139), Ventriculoperitoneal Shunting (MESH:C562451)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12863711/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12863711/full.md

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Source: https://tomesphere.com/paper/PMC12863711