# Efficacy of oblique pulling manipulation combined with adjunct therapies (massage/acupuncture/herbal medicine/injection) for lumbar disc herniation: a systematic review and meta-analysis of pain and functional outcome

**Authors:** Yi Li, Wenhui Li, Yanting Zhang, Meiyu Zhu, Xiaorong Jiang, Xiuqun Cai

PMC · DOI: 10.3389/fneur.2025.1700862 · Frontiers in Neurology · 2026-01-19

## TL;DR

This study finds that oblique pulling manipulation, combined with therapies like massage and acupuncture, improves outcomes for patients with lumbar disc herniation.

## Contribution

The study provides a systematic review and meta-analysis of oblique pulling manipulation combined with adjunct therapies for lumbar disc herniation.

## Key findings

- Oblique pulling manipulation combined with therapies improved effective and cure rates in lumbar disc herniation patients.
- The treatment improved Japanese Orthopedic Association scores and reduced Oswestry Disability Index scores.
- Future research is needed to standardize protocols and assess long-term safety and effectiveness.

## Abstract

This study aimed to systematically evaluate the clinical efficacy of oblique pulling manipulation and its combination with massage, acupuncture, Chinese herbal medicine, and injection therapy in lumbar disc herniation (LDH).

The meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and was registered with PROSPERO (CRD420251107984). A comprehensive search was conducted in databases including China National Knowledge Infrastructure (CNKI), Wanfang Database, Chinese Scientific Journals Database (VIP), Chinese Biomedical Literature Database (CBM), PubMed, EMBASE, Web of Science, and the Cochrane Library until June 2025. All statistical analyses were conducted using Review Manager 5.4.1. Dichotomous outcomes were summarized as odds ratios (ORs) with 95% confidence intervals (CIs), and continuous outcomes were summarized as standardized mean differences (SMDs) with 95% CIs.

A total of 26 studies comprising 2,766 patients with lumbar disc herniation were included. The results of the meta-analysis revealed that oblique pulling manipulation and its combination with massage, acupuncture, Chinese herbal medicine, and injection therapy in LDH significantly improved the effective rate and cure rate in patients with LDH. In addition, oblique pulling manipulation significantly improved the Japanese Orthopedic Association (JOA) score, and oblique pulling manipulation combined with massage or acupuncture decreased the Oswestry Disability Index (ODI).

Oblique pulling manipulation and its combination with massage, acupuncture, Chinese herbal medicine, and injection therapy improved efficacy and cure rates in patients with lumbar disc herniation. Future research should focus on standardizing treatment protocols and extending follow-up periods to confirm long-term safety and effectiveness, thereby ensuring broader applicability and better patient outcomes.

https://www.crd.york.ac.uk/prospero/CRD420251107984, identifier: CRD420251107984.

## Full-text entities

- **Diseases:** LDH (MESH:C535531), pain (MESH:D010146)
- **Chemicals:** Chinese herbal medicine (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12862601/full.md

## References

47 references — full list in the complete paper: https://tomesphere.com/paper/PMC12862601/full.md

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Source: https://tomesphere.com/paper/PMC12862601