# Evolution and surgical management of a Mycobacterium avium complex aortic infection

**Authors:** Fletcher N. Pierce, Gear T. Vincent, Aubrey Mwinyogle, Jean M. Panneton

PMC · DOI: 10.1016/j.jvscit.2025.101763 · Journal of Vascular Surgery Cases, Innovations and Techniques · 2025-02-26

## TL;DR

A patient with a rare Mycobacterium avium complex infection and AIDS successfully underwent complex surgical treatments for aortic aneurysms.

## Contribution

This case highlights a novel surgical approach using a combination of rifampin-impregnated grafts and cryopreserved homografts for managing aortic infections.

## Key findings

- A ruptured thoracoabdominal aneurysm was repaired using a rifampin-impregnated Dacron graft.
- A cryopreserved cadaveric aortic homograft was successfully used for in situ repair after endovascular bridging.

## Abstract

We present a case describing the successful surgical management of both an infected aneurysm and an aortic graft infection in a patient with disseminated Mycobacterium avium complex infection and AIDS. The patient was a 53-year-old man presenting with a ruptured type V thoracoabdominal aortic aneurysm and an isolated 7.1-cm infrarenal abdominal aortic aneurysm. He underwent emergent repair of his ruptured thoracoabdominal aneurysm using a rifampin-impregnated Dacron graft. This was followed by a temporizing endovascular aortic repair and was eventually bridged with an in situ repair using a cryopreserved cadaveric aortic homograft.

## Linked entities

- **Chemicals:** rifampin (PubChem CID 135398735)
- **Diseases:** AIDS (MONDO:0012268)

## Full-text entities

- **Diseases:** Mycobacterium avium complex aortic infection (MESH:D015270), aortic graft infection (MESH:D007239), infected aneurysm (MESH:D000785), abdominal aortic aneurysm (MESH:D017544), thoracoabdominal aneurysm (MESH:D000094624), AIDS (MESH:D000163)
- **Chemicals:** Dacron (MESH:D011093), rifampin (MESH:D012293)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12861941/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12861941/full.md

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Source: https://tomesphere.com/paper/PMC12861941