# OPTEM-oHCM: OPtimal Targeted Polymer-based EMbolization for Obstructive Hypertrophic CardioMyopathy

## TL;DR

A new embolization method using a polymer is shown to effectively treat obstructive hypertrophic cardiomyopathy in a patient where traditional methods were limited.

## Contribution

The paper introduces polymer-based embolization as a novel and precise alternative for treating obstructive hypertrophic cardiomyopathy.

## Key findings

- Targeted embolization with ethylene-vinyl alcohol copolymer resolved the left ventricular outflow tract gradient completely.
- Polymer embolization was effective in a case with atypical blood supply, where traditional methods were not suitable.

## Abstract

Obstructive hypertrophic cardiomyopathy often requires septal reduction in symptomatic patients, but standard alcohol septal ablation may be limited in some cases.

A 72-year-old woman presented with dyspnea and syncope. Investigations revealed dynamic left ventricular outflow tract gradient up to 167 mm Hg. Targeted embolization using ethylene-vinyl alcohol copolymer on septal and circumflex branches achieved complete gradient resolution.

This case demonstrates polymer-based embolization as a feasible alternative for complex cases, offering precise targeting beyond traditional septal branches, aligned with current guidelines for nonsurgical candidates.

Polymer embolization provides effective left ventricular outflow tract relief in obstructive hypertrophic cardiomyopathy with atypical supply. Functional balloon testing optimizes outcomes in high-risk patients.