# Valve-In-Valve TAVI in a Patient With Dextrocardia, Situs Inversus, and Challenging Commissural Alignment

**Authors:** Ho-On Alston Conrad Chiu, Ka-Chun Un, Chun-Ka Wong, Shu-Yue Sze, Ching-Wei Lee, Frankie Chor-Cheung Tam, Kwong-Yue Eric Chan, Daniel Tai-Leung Chan, Gilbert H.L. Tang, Simon Cheung-Chi Lam

PMC · DOI: 10.1016/j.jaccas.2025.105833 · JACC Case Reports · 2025-10-25

## TL;DR

This paper describes a successful valve-in-valve TAVI procedure in a patient with rare heart anatomy, using specialized techniques to align the new valve correctly.

## Contribution

The paper introduces a novel strategy for commissural alignment during ViV-TAVI in patients with dextrocardia and situs inversus.

## Key findings

- Loading the Evolut FX+ C-tab 180° upside down in the delivery catheter facilitated commissural alignment.
- Adjusting the flush-port position to 5-o’clock enabled proper alignment of the TAVI valve with the former prosthesis.
- The former prosthetic valve commissure was oriented 60° from native commissures to preserve coronary access.

## Abstract

Valve-in-valve transcatheter aortic valve implantation (ViV-TAVI) for dextrocardia is challenging. An 81-year-old man with dextrocardia and situs inversus developed prosthetic aortic stenosis. Loading Evolut FX+ C-tab 180° upside down in a delivery catheter facilitates commissural alignment during ViV-TAVI in dextrocardia. To accommodate anatomical variations, the flush-port position can be adjusted. In this case, the flush port was positioned 5-o’clock (60° from the usual 3-o’clock position) to align the TAVI valve with former prosthesis, as the former prosthetic valve commissure was oriented 60° from native commissures to preserve coronary access for abnormal left coronary artery originating from native commissures. This case illustrates strategies for commissural alignment during ViV-TAVI in dextrocardia.

## Full-text entities

- **Diseases:** Situs Inversus (MESH:D012857), aortic stenosis (MESH:D001024), Dextrocardia (MESH:D003914)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12861681/full.md

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Source: https://tomesphere.com/paper/PMC12861681