# The Impact of Moderate to High Intensity Physical Activity on Sleep Health in Cancer Survivors

**Authors:** Grace E. Markey, Julie J. Ruterbusch, Tara E. Baird, Jennifer L. Martin, Ann G. Schwartz, David G. Finlay, Trey Timban, Matthew R. Trendowski, M. Safwan Badr, Kerri Winters‐Stone, Jennifer L. Beebe‐Dimmer

PMC · DOI: 10.1002/cam4.71546 · Cancer Medicine · 2026-02-01

## TL;DR

Moderate to high intensity physical activity improves sleep health in cancer survivors, according to data from two studies.

## Contribution

This study provides empirical evidence linking physical activity to better sleep outcomes in cancer survivors.

## Key findings

- Participants meeting physical activity guidelines had significantly better sleep scores than inactive individuals.
- HIIT participants showed improved insomnia severity scores after physical activity intervention.
- Sleep quality improved modestly in the HIIT group, but sleepiness levels remained unchanged.

## Abstract

Sleep disturbances are common among cancer survivors and negatively impact quality of life. Regular moderate‐ to high‐intensity physical activity may provide a cost‐effective, low‐risk alternative strategy to improve sleep.

Data collected as part of two distinct studies, the Detroit Research On Cancer Survivors (ROCS) cohort and the CrossFit And Physical Activity: A Better Life Experience (CAPABLE) High‐Intensity Interval Training (HIIT) trial, were analyzed to evaluate the association between participation in moderate‐ to high‐intensity physical activity and sleep health. Sleep health was assessed using the Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale (ESS).

Among Detroit ROCS cohort members who completed the supplemental sleep survey at baseline and/or follow‐up (n = 3022), those meeting 2012 American Cancer Society (ACS) physical activity guidelines reported sleep outcomes compared with inactive participants, including lower ISI scores (4.5 vs. 5.9, p < 0.001), lower ESS scores (5.6 vs. 6.6, p < 0.001), and lower PSQI (6.3 vs. 7.9, p < 0.001). In the CAPABLE trial (n = 73), ISI scores improved from 4.5 at baseline to 3.4 at exit (p < 0.001), while PSQI scores showed more modest improvement (6.1 to 5.4, p = 0.063). ESS scores remained unchanged (5.4 to 5.2, p = 0.708).

These findings support the role of moderate‐ to high‐intensity physical activity in improving sleep health in a diverse cancer survivor population. Future research should further refine current methodologies to maximize benefit to survivors and implementation science to increase uptake and promote adherence to evidence‐based guidelines.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** Sleep disturbances (MESH:D012893), Insomnia (MESH:D007319), Cancer (MESH:D009369)

## Full text

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## References

53 references — full list in the complete paper: https://tomesphere.com/paper/PMC12861574/full.md

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Source: https://tomesphere.com/paper/PMC12861574