# Global quality of care trends for lip and oral cavity cancer: A quality of care index analysis, 1990–2021

**Authors:** Yilin Zhang, Wenkai Xu, Haocheng Wang, Liang Mao, Jing Sun

PMC · DOI: 10.1016/j.pmedr.2026.103380 · Preventive Medicine Reports · 2026-01-07

## TL;DR

This study analyzed global trends in lip and oral cavity cancer care quality from 1990 to 2021, finding improvements but persistent disparities linked to socioeconomic factors.

## Contribution

The novel Quality of Care Index (QCI) was developed to assess global disparities in lip and oral cavity cancer care.

## Key findings

- Global care quality improved from 1990 to 2021, but disparities persist.
- High-income regions had high incidence, while low-income areas had high mortality.
- Females consistently had higher care quality scores than males.

## Abstract

To evaluate global trends and disparities in the quality of care for lip and oral cavity cancer (LOCC) from 1990 to 2021 using the Quality of Care Index (QCI).

Data on LOCC burden were obtained from the Global Burden of Disease (GBD) 2021 study, covering 204 countries and territories from 1990 to 2021. The QCI was constructed via principal component analysis of four component indices: mortality-to-incidence ratio, prevalence-to-incidence ratio, years of life lost to years lived with disability ratio, and disability-adjusted life years to prevalence ratio. Analyses were stratified by socio-demographic index (SDI), age, and sex.

A geographical decoupling was observed: high-SDI regions had the highest LOCC incidence, while low-middle SDI regions had the highest mortality. The global QCI improved from 1990 to 2021 but strongly correlated with national development. Females consistently had higher QCI scores than males across all SDI groups. The QCI-age relationship varied by SDI region.

Despite global improvement, significant inequities in LOCC care quality persist across regions, ages, and sexes. Future strategies must focus on enhancing healthcare system performance and ensuring equitable access to effective care.

•Global oral cancer care quality improved from 1990 to 2021.•High incidence in developed regions, high mortality in low-resource areas.•Females consistently had higher care quality scores than males.•Care quality varied by age and socioeconomic development level.•Strong correlation between national development and care quality.

Global oral cancer care quality improved from 1990 to 2021.

High incidence in developed regions, high mortality in low-resource areas.

Females consistently had higher care quality scores than males.

Care quality varied by age and socioeconomic development level.

Strong correlation between national development and care quality.

## Linked entities

- **Diseases:** lip and oral cavity cancer (MONDO:0023644)

## Full-text entities

- **Diseases:** LOCC (MESH:D008048)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12861060/full.md

## References

33 references — full list in the complete paper: https://tomesphere.com/paper/PMC12861060/full.md

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Source: https://tomesphere.com/paper/PMC12861060