# Cocaine-induced midline destructive lesion with extensive cutaneous involvement

**Authors:** Laís Guerra Guedes, Márcio Martins Lobo Jardim, Felipe Marinho Rocha de Macedo, Isabella Cavalcanti Gomes de Sá, Renata Guerra Galvão Santos, Daniela Mayumi Takano

PMC · DOI: 10.1016/j.abd.2025.501277 · Anais Brasileiros de Dermatologia · 2026-01-23

## Full-text entities

- **Genes:** PRTN3 (proteinase 3) [NCBI Gene 5657] {aka ACPA, AGP7, C-ANCA, CANCA, MBN, MBT}
- **Diseases:** vasculitis (MESH:D014657), deformities of the nose and midface (MESH:D009668), inflammation (MESH:D007249), pruritus (MESH:D011537), Necrotic (MESH:D009336), cutaneous leishmaniasis (MESH:D016773), midline destructive lesion (OMIM:613730), NK/T-cell lymphoma (MESH:D016399), ORCID ID (MESH:C537985), CIMDL (MESH:D019970), Necrotic ulcer (MESH:D014456), malignancy (MESH:D009369), rhinorrhea (MESH:D012818), ischemic (MESH:D002545), Wegener's granulomatosis (MESH:D014890)
- **Chemicals:** Hematoxylin (MESH:D006416), eosin (MESH:D004801), x100 (-), Cocaine (MESH:D003042)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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## References

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Source: https://tomesphere.com/paper/PMC12861047