# Chemical and Biological Properties of Hymenaea courbaril L.: A Review

## TL;DR

This review summarizes the chemical composition and biological effects of Hymenaea courbaril, a plant used in traditional medicine for various health conditions.

## Contribution

The paper provides a comprehensive overview of the phytochemicals and validated biological activities of Hymenaea courbaril, highlighting areas for future research.

## Key findings

- Hymenaea courbaril contains bioactive compounds like flavonoids, terpenes, phenols, and coumarins.
- It exhibits antibacterial, antifungal, antiviral, anti-inflammatory, antioxidant, and antiproliferative effects.
- Low acute toxicity was observed in in vivo studies, supporting its potential for medicinal use.

## Abstract

Hymenaea courbaril L., commonly known as jatobá, is a plant traditionally used by native populations for medicinal purposes, in addition to providing edible fruits and durable wood for construction. In Brazilian traditional medicine, products from this species are employed to treat wounds, inflammations, bacterial infections, rheumatism, anemia, respiratory and gastric disorders, bronchitis, and prostate conditions. This review aimed to summarize the phytochemical composition and biological activities of H. courbaril L., establishing a foundation for future studies. The species is rich in bioactive compounds, including flavonoids, terpenes, phenols, and coumarins present in its leaves, fruits, bark, and resin. Scientifically validated bioactivities include antibacterial, antifungal, antiviral, anti‐inflammatory, antioxidant, muscle‐relaxant, and antiproliferative effects. Low acute toxicity has been demonstrated in in vivo assays. Despite these promising results, gaps remain regarding its chemical characterization, medicinal, and nutraceutical potential. This review highlights the need for further research to validate traditional uses, ensure safe applications, and explore new therapeutic prospects.

PRISMA‐style flowchart showing the screening process of studies identified and selected in the review has been added to the attachments.