# Indications and opportunities for transsplenic access to treat portal venous and portosystemic pathology: A report of 2 cases and review of the literature

**Authors:** Trinity Puno, Joshua Levy, Daniel Villegas, Marvi Moreno, Ryan Rimer, Brandon Chen

PMC · DOI: 10.1016/j.radcr.2025.12.053 · 2026-01-24

## TL;DR

This paper discusses the use of transsplenic access as an effective method for treating complex portal venous diseases when traditional approaches are not feasible.

## Contribution

The paper introduces two unique clinical cases demonstrating the effectiveness of transsplenic access in complex portal venous interventions.

## Key findings

- Transsplenic access enabled successful portal vein thrombectomy and shunt placement in a cirrhotic patient with extensive thromboses.
- A combined transsplenic–transhepatic technique facilitated recanalization and shunt creation in a patient with chronic portal vein thrombosis.

## Abstract

Transsplenic access has emerged as a valuable technique for portal venous interventions when conventional transjugular or transhepatic approaches are challenging due to prohibitive anatomy. We briefly summarize the literature on how transsplenic access came to be and present 2 unique cases that highlight the importance of transsplenic access in facilitating transjugular intrahepatic portosystemic shunt creation in complex portal venous disease. The first case describes a 68-year-old male cirrhotic patient with extensive acute-on-chronic portal vein thromboses in whom transsplenic access enabled portal vein thrombectomy and successful portosystemic shunt placement. The second case involves a 60-year-old female patient with chronic portal vein thrombosis and cavernous transformation, where a combined transsplenic–transhepatic “body floss” technique allowed recanalization and subsequent portosystemic shunt creation.

## Linked entities

- **Diseases:** cirrhosis (MONDO:0005155), portal vein thrombosis (MONDO:0001339)

## Full-text entities

- **Diseases:** portal venous disease (MESH:D006975), cirrhotic (MESH:D000094724), portal vein thromboses (MESH:D012170)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12860249/full.md

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Source: https://tomesphere.com/paper/PMC12860249