Developing Normative Reference Values for Nerve Conduction Studies Using Electrophysiological Parameters in the Bangladeshi Population

TL;DR

This study establishes nerve conduction reference values for the Bangladeshi population, showing differences from international data to improve diagnostic accuracy.

Contribution

Provides population-specific normative values for nerve conduction studies in Bangladesh.

Findings

Left median motor nerve has a mean distal latency of 3.01 ± 0.34 ms and conduction velocity of 59.67 ± 6.64 m/s.

Left median sensory nerve shows latency of 2.30 ± 0.25 ms and velocity of 55.87 ± 4.48 m/s.

Reference values differ significantly from international data, highlighting the need for local norms.

Abstract

This study aims to establish normative reference values for nerve conduction studies specific to the Bangladeshi population. Data were collected from 258 healthy subjects, grouped by age and sex. Both motor and sensory nerves of the upper and lower limbs were assessed. Using the ordinary least square (OLS) regression method, it is seen that for the left median motor nerve, the mean distal latency is 3.01 ± 0.34 ms, amplitude 18.05 ± 4.73 μV, and conduction velocity 59.67 ± 6.64 m/s. For the left median sensory nerve, the latency is 2.30 ± 0.25 ms, the amplitude is 60.82 ± 23.95 μV, and the velocity is 55.87 ± 4.48 m/s. The findings of this study were compared with previously published international data, revealing significant differences. These results provide neurophysicians with population‐specific reference values, enhancing diagnostic accuracy, enabling earlier detection of nerve conduction abnormalities, and guiding more targeted and effective treatment strategies for nerve disorders in Bangladesh.

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