# Ablation of AVNRT in a Setting of Slow Pathway–Dominant Conduction

**Authors:** Liuguang Song, Simin Cai, Jian Ye, Yaping Wang

PMC · DOI: 10.1016/j.jaccas.2025.106059 · 2025-12-03

## TL;DR

A 33-year-old man with a specific heart rhythm disorder was successfully treated with ablation of the slow pathway in the heart, preserving normal function of the fast pathway.

## Contribution

This case demonstrates the successful treatment of slow pathway–dominant AVNRT through ablation while preserving fast pathway function.

## Key findings

- Slow pathway ablation successfully treated AVNRT with preserved fast pathway function.
- Isoproterenol administration normalized the prolonged PR interval in sinus rhythm.
- Electrophysiology study revealed conduction abnormalities that resolved post-ablation.

## Abstract

We report a case of paroxysmal supraventricular tachycardia with slow pathway–dominant conduction and prolonged PR interval in sinus rhythm.

A 33-year-old man presented with persistent palpitations and chest tightness, with narrow QRS tachycardia with a prolonged PR interval on electrocardiogram. After the administration of isoproterenol, the PR interval normalized. During the electrophysiology study, atrioventricular node conduction jumping, echoes, and dual ventricular responses were observed. After ablation, the fast pathway function of the atrioventricular node was restored, and electrocardiography revealed a normal PR interval.

This case demonstrates that slow pathway–dominant atrioventricular nodal re-entrant tachycardia can be successfully treated by slow pathway ablation, while ensuring normal fast pathway function is key to avoiding atrioventricular block.

Slow pathway ablation effectively treats this arrhythmia, and the preservation of fast pathway function is crucial to avoid atrioventricular block.

## Linked entities

- **Chemicals:** isoproterenol (PubChem CID 3779)
- **Diseases:** atrioventricular block (MONDO:0000465)

## Full-text entities

- **Diseases:** atrioventricular nodal re-entrant tachycardia (MESH:D013611), tachycardia (MESH:D013610), arrhythmia (MESH:D001145), paroxysmal supraventricular tachycardia (MESH:D017180), atrioventricular block (MESH:D054537), palpitations (MESH:D006331)
- **Chemicals:** isoproterenol (MESH:D007545)

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12859574/full.md

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Source: https://tomesphere.com/paper/PMC12859574