# Auditory dysfunction and perinatal risk factors in high-risk infants: Insights from brainstem evoked response audiometry

**Authors:** Mahima Sharma, Madhuri Sharma, Raghav Mehta, Arpana Singhal, Deepandra Garg

PMC · DOI: 10.6026/973206300213715 · 2025-10-31

## TL;DR

This study shows that high-risk infants are more likely to have hearing issues, linked to factors like jaundice and asphyxia, highlighting the need for early hearing screening.

## Contribution

The study identifies specific perinatal risk factors strongly associated with auditory dysfunction in high-risk infants using BERA.

## Key findings

- 30% of high-risk neonates showed abnormal BERA results.
- Severe hyperbilirubinemia, perinatal asphyxia, and prolonged mechanical ventilation were significantly linked to auditory dysfunction.
- Infants with abnormal BERA had prolonged wave V latency.

## Abstract

Congenital hearing impairment is a major developmental disability, especially among infants with perinatal risk factors. This
cross-sectional study evaluated 150 high-risk neonates in a NICU using Brainstem Evoked Response Audiometry (BERA). Abnormal BERA
findings were observed in 30% of infants, with significant associations to severe hyperbilirubinemia, perinatal asphyxia and prolonged
mechanical ventilation (p<0.001). Mean wave V latency was notably prolonged in infants with abnormal results. Thus, we show the
importance of universal newborn hearing screening, particularly in high-risk groups, to enable early diagnosis and timely intervention.

## Linked entities

- **Diseases:** perinatal asphyxia (MONDO:0006663)

## Full-text entities

- **Diseases:** Auditory dysfunction (MESH:D006311), hyperbilirubinemia (MESH:D006932), perinatal asphyxia (MESH:D001237), Congenital hearing impairment (MESH:D034381), developmental disability (MESH:D002658)

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Source: https://tomesphere.com/paper/PMC12859376