# Comparative evaluation of apical microleakage in bioceramic and epoxy resin-based sealers using dye penetration and SEM analysis: An in vitro study

**Authors:** Abdullah Abdullatif Mahdi, Anshad Zaheer, Nabeela Najeeb A.P, Krishnan Hari, Ranjith K, Rajani E.R

PMC · DOI: 10.6026/973206300213861 · 2025-10-31

## TL;DR

This study compares bioceramic and epoxy resin-based sealers for their ability to prevent microleakage in root canal treatments.

## Contribution

The study provides new empirical evidence on the superior sealing performance of bioceramic sealers over epoxy resin-based ones.

## Key findings

- Bioceramic sealers showed significantly less dye penetration (1.42 ± 0.23 mm) compared to epoxy resin-based sealers (2.68 ± 0.31 mm).
- SEM analysis revealed better interfacial adaptation and fewer gaps with bioceramic sealers.
- Epoxy resin-based sealers exhibited more voids and detachment from the dentin.

## Abstract

Root canal therapy success depends on achieving a hermetic apical seal to prevent microbial reinfection. Sealers play a crucial role
in minimizing microleakage and ensuring long-term treatment success. In this study of forty extracted teeth, a bioceramic sealer
demonstrated significantly less dye penetration (1.42 ± 0.23 mm) than an epoxy resin-based sealer (2.68 ± 0.31 mm, p < 0.
05). Scanning electron microscopy revealed superior interfacial adaptation with fewer gaps in the bioceramic group, while epoxy resin-
based sealers showed more voids and detachment. These findings indicate that bioceramic sealers provide improved sealing and adaptation
to dentin, enhancing the apical seal quality in endodontic therapy.

## Full-text entities

- **Chemicals:** epoxy resin (MESH:D004853)

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Source: https://tomesphere.com/paper/PMC12859291