# Severity of diabetic retinopathy severity with renal function and body fat in type 2 diabetes mellitus: A hospital-based cross-sectional study in India

**Authors:** Alwin Kurian Raju, Jojo Pullockara1, Thomas Cheriyan

PMC · DOI: 10.6026/973206300213990 · 2025-10-31

## TL;DR

This study explores how severe diabetic retinopathy is linked to kidney function and body fat in type 2 diabetes patients in India.

## Contribution

The study reveals new insights into the inter-relationships between retinopathy, renal function, and body fat in type 2 diabetes.

## Key findings

- DR severity correlates with worsening kidney function and higher body fat percentage.
- The findings highlight the need for early screening to manage diabetes complications comprehensively.

## Abstract

Diabetic retinopathy (DR) severity and renal impairment are important complications of type 2 diabetes mellitus. However, the
relationship between them and body fat percentage (BFP) is not known. Hence, a cross-sectional study was conducted on 166 patients aged
30-70 years that measured DR severity, renal function and body fat percentage (BFP) using traditional clinical and anthropometric
assessments. This data shows DR severity was related to measurable deterioration in renal parameters and raised body fat percentage
(BFP). Thus, we show the understanding of the inter-relationships between microvascular and metabolic-related complications of diabetes.
Increased screening earlier may help risk stratify and potentially facilitate comprehensive management of the patient in the clinical
setting.

## Linked entities

- **Diseases:** diabetic retinopathy (MONDO:0005266), type 2 diabetes mellitus (MONDO:0005148)

## Full-text entities

- **Diseases:** type 2 diabetes mellitus (MESH:D003924), renal impairment (MESH:D007674), diabetes (MESH:D003920), DR (MESH:D003930)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12859273