# Comparative evaluation of transforaminal lumbar interbody fusion and instrumented posterolateral fusion in Grade I/II Spondylolisthesis: A prospective study

**Authors:** Abhiranjan Prasad, Narendra Kumar Das, Sourabh Guria, Diptiranjan Satapathy

PMC · DOI: 10.6026/973206300213426 · 2025-10-31

## TL;DR

This study compares two spinal fusion surgeries for spondylolisthesis, finding each has unique benefits in recovery and pain relief.

## Contribution

The study provides a prospective comparison of TLIF and PLF outcomes in Grade I/II spondylolisthesis patients.

## Key findings

- PLF showed better 6-month functional outcomes and greater slip reduction compared to TLIF.
- TLIF provided better early leg pain relief and higher DPQ scores at 3 months.
- Complication and fusion rates were similar between the two surgical techniques.

## Abstract

The optimal surgical approach between Transforaminal Lumbar Interbody Fusion (TLIF) and Posterolateral Fusion (PLF) for Grade I/II
spondylolisthesis remains unclear. Therefore, it is of interest to compare clinical and radiological outcomes of TLIF versus PLF in
patients with Grade I/II spondylolisthesis. PLF achieved better 6-month functional outcomes (ODI 12.95 ± 2.54 vs 17.83 ±
1.95, p<0.001) and greater slip reduction (48.45% vs 40.20%, p<0.001). TLIF provided superior early leg pain relief at 3 months
(VAS 2.03 ± 0.80 vs 2.50 ± 0.91, p=0.015) and better DPQ scores. Complication and fusion rates were similar between groups.
Both techniques are effective, with choice guided by patient profile and clinical priorities.

## Linked entities

- **Diseases:** spondylolisthesis (MONDO:0008475)

## Full-text entities

- **Diseases:** pain (MESH:D010146), Spondylolisthesis (MESH:D013168), slip (MESH:D004839)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12859271