# Severe Phytophotodermatitis Caused by Mulberry Tree: A Case Report and Literature Review

**Authors:** Young Geun Kim, Keun-Cheol Lee

PMC · DOI: 10.1055/a-2699-8042 · Archives of Plastic Surgery · 2026-01-30

## TL;DR

A 52-year-old man developed a severe skin reaction after contact with a mulberry tree, highlighting the importance of diagnosing phytophotodermatitis correctly.

## Contribution

This case report highlights the clinical presentation and management of severe phytophotodermatitis caused by mulberry tree exposure.

## Key findings

- The patient's symptoms were misdiagnosed as cellulitis before the correct diagnosis of phytophotodermatitis was made.
- Oral and topical corticosteroids effectively treated the severe phytophotodermatitis.
- A detailed patient history and biopsy confirmed the diagnosis of phytophotodermatitis.

## Abstract

Phytophotodermatitis (PPD) is an uncommon dermatologic condition that occurs after exposure to furocoumarins found in certain plant saps, which become activated upon ultraviolet A radiation exposure. This condition is frequently misdiagnosed as cellulitis, allergic dermatitis, or other common skin disorders. Here, we present a case of severe PPD in a 52-year-old male who initially developed a rash and blistering on his forearm following outdoor activity. He was initially misdiagnosed with cellulitis; however, his symptoms persisted despite antibiotic treatment, prompting further evaluation. A detailed patient history revealed recent contact with a mulberry tree, and together with characteristic biopsy findings, confirmed the diagnosis of PPD. The patient showed significant improvement following the administration of oral corticosteroids and topical steroid treatment. This case underscores the importance of recognizing PPD in clinical practice to prevent misdiagnosis and ensure effective management.

## Linked entities

- **Diseases:** cellulitis (MONDO:0005230)

## Full-text entities

- **Diseases:** skin disorders (MESH:D012871), cellulitis (MESH:D002481), dermatologic condition (MESH:D000168), allergic dermatitis (MESH:D017449), blistering (MESH:D001768), rash (MESH:D005076)
- **Chemicals:** furocoumarins (MESH:D011564), steroid (MESH:D013256), ultraviolet A (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12858321/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12858321/full.md

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Source: https://tomesphere.com/paper/PMC12858321