# A case of gastric gastrointestinal stromal tumour with two rare metastases after laparoscopic resection and imatinib therapy

**Authors:** Nathan J Bui, Hai T Bui

PMC · DOI: 10.1093/jscr/rjag024 · Journal of Surgical Case Reports · 2026-01-30

## TL;DR

A man with a stomach tumor developed rare metastases in his skin and muscle after surgery and drug treatment, showing the need for long-term monitoring.

## Contribution

Highlights an unusual metastatic pattern in gastrointestinal stromal tumors following standard treatment.

## Key findings

- Patient developed metastases to subcutaneous tissue and skeletal muscle after initial treatment.
- Emphasizes the importance of long-term surveillance for gastrointestinal stromal tumor recurrence.
- Demonstrates atypical metastatic behavior not commonly reported in literature.

## Abstract

We report the case of a 70-year-old man with a gastric gastrointestinal stromal tumour who subsequently developed two rare metastatic recurrences to the subcutaneous tissue and skeletal muscle following initial curative resection and adjuvant imatinib therapy. This case illustrates the potential for atypical metastatic patterns in gastrointestinal stromal tumour and emphasizes the importance of long-term surveillance, even after extended disease-free intervals.

## Linked entities

- **Chemicals:** imatinib (PubChem CID 5291)

## Full-text entities

- **Diseases:** metastases (MESH:D009362), gastric gastrointestinal stromal tumour (MESH:D046152)
- **Chemicals:** imatinib (MESH:D000068877)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12857201/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12857201/full.md

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Source: https://tomesphere.com/paper/PMC12857201