# Executive Summary of the 2024 Philippine Clinical Practice Guidelines on the Diagnosis and Management of Acute Severe Blood Pressure Elevation

**Authors:** Deborah Ignacia D. Ona, Felix Eduardo Punzalan, Raymond V. Oliva, Ma. Sergia Fatima Sucaldito, Noel Espallardo, Richard Santos, Hannah Almenario, Karl Murillo, Valentin Dones, Elmer Jasper Llanes, Lourdes Ella Santos, Maria Cristina San Jose, Alyssa Samantha Fusingan‐Peralta, Rommel Bataclan, Maria Katrina Mata, Pauline Convocar, Aurelia Leus, Gilbert Vilela

PMC · DOI: 10.1111/jch.70199 · The Journal of Clinical Hypertension · 2026-01-30

## TL;DR

The 2024 Philippine Clinical Practice Guidelines address the rising hypertension issue by providing evidence-based recommendations for diagnosing and managing severe blood pressure elevation.

## Contribution

The paper introduces the first Philippine-specific clinical guidelines for managing severe acute blood pressure elevation, addressing a critical knowledge gap.

## Key findings

- Hypertension prevalence in the Philippines increased from 22% in the 1990s to 37% in 2021.
- Only 37% of hypertensive patients achieved blood pressure control despite high treatment and adherence rates.
- The 2024 guidelines provide 11 recommendations and 4 best practice statements for managing severe BP elevation.

## Abstract

A recent survey in the Philippines, PRESYON‐4, showed increasing prevalence of hypertension from 22% in the 1990s to 37% in 2021, of which only 52% were aware of their diagnosis. While rates of treatment and adherence were 68% and 86%, respectively, the rate of BP control was low at 37%. Furthermore, there remained a high degree of unawareness regarding hypertension, its role in CV morbidity and mortality, and how it can be optimally managed. In particular, there is a knowledge gap in the diagnostic approach and management of severe acute elevations in blood pressure. In response to this, the Philippine Society of Hypertension, Philippine Heart Association, and multiple experts from various sectors worked together to develop the 2024 Clinical Practice Guideline on the Diagnosis and Management of Severe Blood Pressure Elevation. The CPG provides eleven (11) recommendations and four (4) best practice statements addressing key clinical questions on the diagnosis and management of severe BP elevation. The guideline development process adhered to the GRADE approach through the Evidence to Decision (EtD2) framework, including the identification of critical questions and outcomes, retrieval of current evidence, appraisal and synthesis of the evidence, and formulation of draft recommendations. A multisectoral consensus panel (CP) was convened to discuss values, preferences, and socioeconomic impact and finalize the strength of the recommendations. The CPG is intended to be used by general practitioners, specialists, family physicians, allied health professionals, emergency medical personnel, and healthcare workers who may encounter adult patients with hypertension, whether in the inpatient or outpatient setting.

## Full-text entities

- **Genes:** BCL2A1 (BCL2 related protein A1) [NCBI Gene 597] {aka ACC-1, ACC-2, ACC1, ACC2, BCL2L5, BFL1}
- **Diseases:** DBP (OMIM:261515), dyspnea (MESH:D004417), HMOD (MESH:D006973), tachycardia (MESH:D013610), vomiting (MESH:D014839), cerebrovascular disease (MESH:D002561), watershed infarcts (MESH:D007238), acute stroke (MESH:D020521), hyperlipidemia (MESH:D006949), blurred vision (MESH:D014786), acute pulmonary edema (MESH:D011654), ACS (MESH:D054058), subarachnoid hemorrhage (MESH:D013345), bleeding (MESH:D006470), hypotension (MESH:D007022), thrombotic microangiopathy (MESH:D057049), ICH (MESH:D002543), substance abuse (MESH:D019966), neurologic deterioration (MESH:D009422), proteinuria (MESH:D011507), hemolysis (MESH:D006461), end-organ damage (MESH:C564816), edema (MESH:D004487), chest pain (MESH:D002637), congestive heart failure (MESH:D006333), death (MESH:D003643), MACE (MESH:D002318), dizziness (MESH:D004244), ASCVD (MESH:D050197), HELLP (MESH:D017359), headache (MESH:D006261), ED (MESH:D004630), depressed (MESH:D003866), NCD (MESH:D000073296), atrial fibrillation (MESH:D001281), damage (MESH:D020263), diabetes (MESH:D003920), pulmonary congestion (MESH:D001261), hematoma (MESH:D006406), arrhythmia (MESH:D001145), renal dysfunction (MESH:D007674), anxiety (MESH:D001007), acute target organ damage (MESH:D000208), Myocardial infarction (MESH:D009203), chronic kidney disease (MESH:D051436), acute ischemic stroke (MESH:D000083242), aortic dissection (MESH:D000784), IHD (MESH:D017202), coronary artery disease (MESH:D003324), pain (MESH:D010146)
- **Chemicals:** nitroprusside (MESH:D009599), diazoxide (MESH:D003981), carperitide (MESH:C472955), hydralazine (MESH:D006830), nifedipine (MESH:D009543), clevidipine (MESH:C118563), enalapril (MESH:D004656), metoprolol (MESH:D008790), glyceryl trinitrate (MESH:D005996), Labetalol (MESH:D007741), dopamine (MESH:D004298), nitrates (MESH:D009566), furosemide (MESH:D005665), amlodipine (MESH:D017311), clonidine (MESH:D003000), isosorbide dinitrate (MESH:D007548), opiates (MESH:D053610), BP (MESH:C038809), captopril (MESH:D002216), isosorbide (MESH:D007547), Nicardipine (MESH:D009529), urapidil (MESH:C015568)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

55 references — full list in the complete paper: https://tomesphere.com/paper/PMC12856959/full.md

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Source: https://tomesphere.com/paper/PMC12856959