# Eosinophilic Colitis in an Adult Ethiopian Patient

**Authors:** Kaleb Assefa Berhane, Ahmed Adem, Abate Bane Shewaye, Nathan Tolemariam Jibat, Lela Alemayehu Gebeyehu, Fadil Nuredin Abrar

PMC · DOI: 10.1155/crgm/1279031 · Case Reports in Gastrointestinal Medicine · 2026-01-30

## TL;DR

A 48-year-old Ethiopian man with a history of allergies was diagnosed with a rare condition called eosinophilic colitis and successfully treated with prednisolone.

## Contribution

This case report adds to the limited literature on eosinophilic colitis in adult Ethiopian patients.

## Key findings

- The patient's symptoms and biopsy results confirmed a diagnosis of eosinophilic colitis.
- Treatment with oral prednisolone led to full resolution of symptoms.
- The patient had a history of atopic disease, which may be a contributing factor.

## Abstract

Eosinophilic colitis (EC) is a rare subtype of eosinophilic gastrointestinal disorders, marked by dense eosinophilic infiltration of the colon in the absence of secondary causes. We report the case of a 48‐year‐old Ethiopian man with a history of atopic disease who presented with chronic nonbloody diarrhea, intermittent abdominal pain, and fatigue. Diagnostic colonoscopy with biopsy confirmed EC, supported by peripheral eosinophilia and histological findings. The patient was treated with oral prednisolone, leading to complete symptom resolution.

## Linked entities

- **Chemicals:** prednisolone (PubChem CID 5755)
- **Diseases:** eosinophilic colitis (MONDO:0018439)

## Full-text entities

- **Diseases:** diarrhea (MESH:D003967), abdominal pain (MESH:D015746), eosinophilic gastrointestinal disorders (MESH:D005767), eosinophilia (MESH:D004802), fatigue (MESH:D005221), EC (MESH:D003092), atopic disease (MESH:D006969)
- **Chemicals:** prednisolone (MESH:D011239)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12856692/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12856692/full.md

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Source: https://tomesphere.com/paper/PMC12856692