Applications of Multifunctional Hydrogel in Tissue Engineering and Regenerative Medicine
Jieran Lyu, Xuemiao Liu, Qiqi Yang, Yuchang Zhang, Xing Wang
TL;DR
This paper reviews how multifunctional hydrogels can be used to support tissue repair and regenerative medicine by mimicking natural tissues and delivering multiple therapeutic functions.
Contribution
The paper provides a comprehensive review of multifunctional hydrogels, emphasizing their potential in addressing complex tissue repair challenges.
Findings
Hydrogels mimic extracellular matrix and offer structural and biochemical support for tissue repair.
Multifunctional hydrogels integrate drug delivery, infection prevention, and stimulus responsiveness for wound healing.
The review highlights the need for cost-effective and clinically applicable hydrogels for broader use in regenerative medicine.
Abstract
Hydrogels, with excellent hydrophilicity and high‐water content, have emerged as highly versatile biomaterials for tissue engineering and regenerative medicine. On account of the natural mimicry of extracellular matrix (ECM), moisture retention, porosity, biocompatibility, biodegradability, and tunable functionality, they provide crucial structural and biochemical support for tissue repair. As chronic wounds, aging, and degenerative diseases continue to increase, hydrogels offer great potential to overcome the limitations of traditional therapies. Despite these developments, there remains a crucial need for hydrogels that can effectively address the complex, multiphase nature of tissue repair while being cost‐effective and easily applicable in various clinical settings. This review begins by taking wound healing as a representative example, particularly elaborating on the process of…
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Taxonomy
TopicsWound Healing and Treatments · Hydrogels: synthesis, properties, applications · Tissue Engineering and Regenerative Medicine