# Cherenkov emission–based quality assurance for linear accelerators

**Authors:** Hiroyuki Okamoto, Fuma Tojo, Kazuyoshi Kurita, Miyuki Murata, Masataka Ueda, Aya Shimoike, Yuka Kondou, Yukio Fujita, Yuna Nakajima, Satoshi Nakamura, Kotaro Iijima, Takahito Chiba, Hiroki Nakayama, Tetsu Nakaichi, Hiroshi Igaki

PMC · DOI: 10.1093/jrr/rraf072 · 2026-01-13

## TL;DR

This paper introduces a new quality assurance method for linear accelerators using Cherenkov emission to measure treatment accuracy and machine parameters.

## Contribution

A novel CE-based QA phantom and method for real-time evaluation of treatment position, gantry angle, and photon energy in radiotherapy.

## Key findings

- CE-based QA achieved positional accuracy within ±1 mm and gantry angle accuracy within 1°.
- TPR20,10 measured via CE matched ionization chamber results closely.
- CE counts showed higher variation, indicating a need for further investigation.

## Abstract

When electrons exceed the speed of light in a medium, they emit low-intensity visible light, known as Cherenkov emission (CE). This study proposes a novel CE-based quality assurance (QA) test for linear accelerators. A CE-based QA (C-QA) phantom incorporating a mock tumor and four CE observation plates (top, bottom, left, and right) was developed. After tumor-based alignment using cone-beam computed tomography (CBCT), lateral and posterior fields were used for irradiation. A C-Dose camera was employed to measure the treatment position, gantry angle, photon energy (TPR20,10), and CE counts for both fields. The treatment position and TPR20,10 were determined by analyzing the changes in the CE profile, while the gantry angle was calculated based on the tilt between the entry and exit field positions. Confidence limits were evaluated over a three-month period, during which long-term testing demonstrated favorable results. The standard deviations (σ) for CBCT-based positional accuracy and gantry angle were within ±1 mm in all three directions and within 1°, respectively. The mean ± σ for TPR20,10 was 0.631 ± 0.004, closely matching the 0.629 measured using an ionization chamber. Detected CE counts exhibited a higher variation (σ = 2.7%). CE-based QA appears to be an effective and reliable method for radiotherapy. Treatment position could be directly measured without conventional dosimetric devices, while CE imaging simultaneously evaluated positional accuracy, gantry angle, and photon energy (TPR20,10). However, accurate assessment of linear accelerator dose output remains a challenge, and the quantification of CE counts requires further investigation.

## Full-text entities

- **Diseases:** CE (MESH:D014012), Cancer (MESH:D009369), CL (MESH:D002971)
- **Chemicals:** tungsten (MESH:D014414), ABS resin (MESH:C024636), Water (MESH:D014867)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12856039/full.md

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Source: https://tomesphere.com/paper/PMC12856039