PIC-SURE: an open-source platform for integrating clinical and genomic data
Alba Gutiérrez-Sacristán, Emily E. Hughes, Ryan Amari, George Colon, Thomas N. DeSain, Sharra Neely, James T. Peck, Samantha Piatt, Lucas Sikina, Jessica Lyons, Danielle Pillion, Paul Avillach
TL;DR
PIC-SURE is an open-source platform that helps researchers analyze large clinical and genomic datasets in real time.
Contribution
The platform introduces a scalable and reproducible system for integrated clinical and genomic data analysis.
Findings
PIC-SURE supports real-time cohort building across 1.4 million participants from 273 studies.
The platform provides a graphical interface and API for exploring and analyzing complex datasets.
It lowers the barrier for integrated clinical and genomic data analysis.
Abstract
PIC-SURE is an open-source platform for integrating and analyzing large-scale clinical and genomic data. Part of the NIH NHLBI BioData Catalyst® ecosystem, PIC-SURE enables real-time cohort building and analysis across 1.4 M participants within 273 studies (May 2025). Through a graphical interface and API, researchers can explore and analyze complex datasets in real time. This flexibility supports scalable and reproducible research, lowering the barrier to integrated clinical and genomic data analysis.
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Taxonomy
TopicsBioinformatics and Genomic Networks · Single-cell and spatial transcriptomics · Genetic Associations and Epidemiology