Microbial Primer: Ancientbiotics – making modern antimicrobials from historical infection remedies
Freya Harrison, Oluwatosin Q. Orababa
TL;DR
This paper explores using historical infection remedies to discover new antimicrobial treatments by testing their effectiveness.
Contribution
The novel approach is reconstructing and testing historical remedies for potential modern antimicrobial applications.
Findings
Historical remedies may contain antimicrobial properties useful for modern treatments.
Reconstructing these remedies could lead to the discovery of new molecular cocktails for infections.
Abstract
The modern antibiotic era began in the early twentieth century, but humans have long used materials from the natural world to attempt to treat the symptoms of infection. In this primer, we will discuss the rationale for attempting to reconstruct historical infection remedies in order to assess their antimicrobial activity and how this approach could aid the discovery of molecular cocktails with potential for development into novel treatments for infection.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsHistorical Medical Research and Treatments · Paleopathology and ancient diseases · Water management and technologies