# Bridging the gap in the UK’s National Health Service integrated care systems: insights from a mixed methods implementation evaluation of UCLP-PRIMROSE, a care innovation to reduce physical health inequalities for people with severe mental illness

**Authors:** Philippa Shaw, Zuneera Khurshid, Danielle Lamb, Fiona A Stevenson, Gregor Russell, Kristian Hudson, Nirandeep Rehill, Gemma Copsey, Matt Kearney, Edward Beveridge, Ian Prenelle, David Osborn

PMC · DOI: 10.1136/bmjopen-2025-105511 · 2026-01-27

## TL;DR

This study evaluates how well a new care model, UCLP-PRIMROSE, can be implemented in the UK NHS to improve physical health for people with severe mental illness.

## Contribution

The study provides insights into the implementation challenges and facilitators of a care innovation in the context of NHS integrated care systems.

## Key findings

- UCLP-PRIMROSE implementation varied in completeness and consistency across general practices.
- Factors like immature integrated care systems and limited resources hindered embedding the model.
- Successful implementation was driven by staff alignment with the model and supportive system leaders.

## Abstract

We aimed to determine whether UCLP-PRIMROSE (a care innovation to reduce physical health inequalities for people with severe mental illness) could be set up in the current UK National Health Service (NHS) context and identify the processes, barriers and facilitators to implementation.

We employed a convergent mixed methods approach, combining interviews, ethnographic site visits and the collection of meeting notes and uptake data for core model components. Interview transcripts were analysed using reflexive thematic analysis, and all qualitative data, including interview transcripts, were analysed using the Consolidated Framework for Implementation Research. Qualitative work and insights from implementation uptake frequencies were integrated using Normalisation Process Theory.

We evaluated implementation in Yorkshire and three London boroughs, mainly within general practices.

We conducted interviews with 39 staff members who were implementing and/or delivering UCLP-PRIMROSE.

UCLP-PRIMROSE is an integrated evidence-based care pathway developed to reduce cardiovascular disease risk and mental health relapse in people with severe mental illness.

Adaptation and delivery varied in completeness and consistency across 24 general practices and their wider care teams. Factors outside the implementation teams’ influence challenged the embedding of UCLP-PRIMROSE. Factors included the impact from the immaturity of NHS integrated care systems, unintended consequences of the incentivised NHS severe mental illness physical health check and limited capacity for implementing in a system facing resourcing challenges. Drivers of successful implementation included staff being aligned with the values of the UCLP-PRIMROSE model and system leaders acting as champions. Supportive foundational processes acted as facilitators: these included protected and prioritised time for reflection, learning and problem solving.

Implementation of UCLP-PRIMROSE was moderately successful in a relatively short period of time. At the end of the research, all teams wanted to sustain delivery. However, further pathway simplification and additional resources are required to spread UCLP-PRIMROSE beyond early pockets of good practice.

## Linked entities

- **Diseases:** cardiovascular disease (MONDO:0004995)

## Full-text entities

- **Diseases:** schizophrenia (MESH:D012559), long-term conditions (MESH:D000088562), mental illness (MESH:D001523), diabetes (MESH:D003920), COVID-19 (MESH:D000086382), SMI (MESH:D045169), bipolar disorder (MESH:D001714), PRIMROSE (MESH:C536420), CVD (MESH:D002318), deaths (MESH:D003643), mental (MESH:D008607)
- **Chemicals:** sugar (MESH:D000073893)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12853453/full.md

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Source: https://tomesphere.com/paper/PMC12853453