# Type-specific effects of orofacial pain on sleep quality: a cross-sectional clinical study

**Authors:** Sümeyye Coşgun-Baybars, Merve Hacer Talu, Hacer Yalçin, Dicle Gökdemir

PMC · DOI: 10.22514/jofph.2026.011 · 2026-01-12

## TL;DR

This study found that certain types of orofacial pain, like neuropathic and mucosal pain, significantly worsen sleep quality, with gender and age also playing a role.

## Contribution

The study identifies type-specific effects of orofacial pain on sleep quality, highlighting neuropathic and mucosal/cutaneous pain as most impactful.

## Key findings

- Neuropathic and mucosal/cutaneous pain groups had significantly higher sleep disturbance scores.
- Females reported worse sleep latency, disturbances, and daytime dysfunction than males.
- Age showed weak but significant correlations with specific sleep parameters.

## Abstract

Background: This study aimed to assess the impact of different types of 
orofacial pain on sleep quality and to examine the influence of age and gender on 
sleep-related parameters. Methods: In this cross-sectional study, 400 
patients with orofacial pain presenting to the Faculty of Dentistry, Fırat 
University, were included. Participants were divided into eight pain categories: 
pulpal, periodontal, impacted tooth-related, dental implant-related, 
temporomandibular disorder-related, mucosal/cutaneous, neuropathic, and 
oncologic. Pain intensity was measured using the Numeric Rating Scale, and sleep 
quality was assessed via the Pittsburgh Sleep Quality Index (PSQI). 
Non-parametric tests and correlation analyses were used for statistical 
evaluation. Results: The mean age was 33.62 ± 13.06 years, and 
66.8% were female. The mean global PSQI score was 5.56 ± 2.84. Neuropathic 
and mucosal/cutaneous pain groups demonstrated significantly higher PSQI scores, 
especially in sleep latency and disturbances (p < 0.05). Females had 
significantly higher scores in sleep latency, disturbances, and daytime 
dysfunction than males (p < 0.05). Age was weakly but significantly 
correlated with several PSQI components. Conclusions: Neuropathic and 
mucosal/cutaneous pain types were associated with the most detrimental effects on 
sleep quality. Gender and age were also found to influence specific sleep 
parameters.

## Full-text entities

- **Diseases:** pemphigus vulgaris (MESH:D010392), herpes infections (MESH:D007239), DC (MESH:D054221), periodontal (MESH:D010518), visceral pain (MESH:D059265), trigeminal nerve injury (MESH:D061221), psychiatric illness (MESH:D001523), concentration  difficulties (MESH:C567712), Oncologic pain (MESH:D000072716), mucosal (MESH:D052016), neuroinflammation (MESH:D000090862), tenderness (MESH:D063806), ulcers (MESH:D014456), bruxism (MESH:D002012), trigeminal neuralgia (MESH:D014277), cancer (MESH:D009369), fatigue (MESH:D005221), sleep apnea (MESH:D012891), chronic pain (MESH:D059350), -related (MESH:D019973), Neuropathic (MESH:D009437), acute pain (MESH:D059787), oral lichen planus (MESH:D017676), bone  loss (MESH:D001847), depression (MESH:D003866), Headache (MESH:D006261), postoperative pain (MESH:D010149), sleep irregularities (MESH:D008599), mucosal diseases (MESH:D004194), Orofacial pain (MESH:D005157), chronic sleep disorder (MESH:D012893), Pulpal pain (MESH:D003784), peri-implantitis (MESH:D057873), TMD (MESH:D013705), sleep fragmentation (MESH:D012892), lesions (MESH:D009059), acute lymphoblastic leukemia (MESH:D054198), burning mouth syndrome (MESH:D002054), TMJ-OA (MESH:D013706), daytime  dysfunction (MESH:D006970), sleep  disruption (MESH:D019958), and  cutaneous pain (MESH:D010146), inflammation (MESH:D007249), Insomnia (MESH:D007319), anxiety (MESH:D001007), Dysfunction (MESH:D006331)
- **Chemicals:** progesterone (MESH:D011374)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12853164/full.md

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Source: https://tomesphere.com/paper/PMC12853164