# Draft genome sequence of a non-tuberculous Mycobacterium strain isolated from a clinical urine sample

## TL;DR

The paper presents a new Mycobacterium genome from a urine sample, showing unique antimicrobial resistance traits and suggesting it may be a new species.

## Contribution

The study provides a draft genome of a novel Mycobacterium species with distinct antimicrobial resistance characteristics.

## Key findings

- The isolate has a genome of 6,749,454 bp with 6,336 protein CDSs.
- ANI analysis suggests it is a novel species, closely related to Mycobacterium vanbaalenii PYR-1.
- The isolate exhibits a unique antimicrobial resistance profile.

## Abstract

Here, we report the draft sequence of a rapid-growing nontuberculous Mycobacterium isolated from a urine sample at the Scottish Mycobacteria Reference Laboratory, Royal Infirmary of Edinburgh, UK. The reported genome has a length of 6,749,454 bp, a G+C content of 67.2 mol% and 6,336 protein CDSs. Average nucleotide identity (ANI) analysis identified Mycobacterium vanbaalenii PYR-1 as the closest relative (83.32% ANI), indicating that this isolate likely represents a novel species within the genus. Notably, phenotypic characterization revealed a distinct antimicrobial resistance (AMR) profile. This assembly provides a valuable resource for studying the evolution of AMR mechanisms in nontuberculous mycobacteria and offers insight into resistance phenotypes observed in clinical isolates.