# Fetal MRI: abdominal cystic lesions

**Authors:** David García Castellanos, Manuel Recio Rodríguez, Lucía Sanabria Greciano, Alejandra Aguado del Hoyo, Alejandro Díaz Moreno, Julia López Alcolea, Carolina Sampietro, Vicente Martínez de Vega

PMC · DOI: 10.1186/s13244-025-02169-1 · 2026-01-28

## TL;DR

Fetal MRI improves the diagnosis of abdominal cystic lesions in unborn babies, offering better accuracy than ultrasound alone.

## Contribution

The study demonstrates fetal MRI's role in enhancing diagnostic confidence and guiding clinical decisions for abdominal cystic lesions.

## Key findings

- Fetal MRI provides superior soft tissue contrast and multiplanar imaging for lesion characterization.
- MRI findings correlate with prenatal ultrasound and postnatal outcomes, improving diagnostic accuracy.
- Fetal MRI aids in prenatal counseling and surgical planning for better neonatal outcomes.

## Abstract

Fetal MRI has become an essential tool for evaluating abdominal cystic lesions detected on prenatal ultrasound, offering superior soft tissue contrast and multiplanar imaging capabilities. This observational case series, conducted at Quironsalud Madrid University Hospital, analyzed fetuses diagnosed with abdominal cystic lesions who underwent fetal MRI. Lesions were classified into gastrointestinal, genitourinary, teratomatous, and syndromic categories. Fetal MRI allowed for precise lesion characterization, differentiating cystic masses from solid or mixed lesions, and identifying associated structural abnormalities. MRI findings were correlated with fetal ultrasound and, when available, postnatal imaging or surgical outcomes, demonstrating complementary information and improved diagnostic confidence compared to ultrasound alone. This improved accuracy has direct clinical implications, aiding in prenatal counseling, optimizing perinatal management, and guiding postnatal surgical planning. Our results reinforce the role of fetal MRI as a complementary imaging modality for refining the diagnosis of congenital abdominal cystic lesions and improving neonatal outcomes.

This article critically evaluates the role of fetal MRI, in conjunction with prenatal ultrasound, in characterizing abdominal cystic lesions, highlighting its diagnostic advantages over ultrasound and its clinical impact on prenatal counseling, perinatal management, and postnatal surgical planning in radiological practice.

Abdominal cystic lesions are frequently detected on prenatal ultrasound, but their characterization and differentiation remain challenging.Fetal MRI characterizes lesions, assesses their extent, improves classification and diagnosis, and offers superior soft tissue contrast for evaluating complex anomalies.Fetal MRI complements prenatal ultrasound, allowing a more precise assessment of lesion characteristics and facilitating prenatal counseling and perinatal planning.

Abdominal cystic lesions are frequently detected on prenatal ultrasound, but their characterization and differentiation remain challenging.

Fetal MRI characterizes lesions, assesses their extent, improves classification and diagnosis, and offers superior soft tissue contrast for evaluating complex anomalies.

Fetal MRI complements prenatal ultrasound, allowing a more precise assessment of lesion characteristics and facilitating prenatal counseling and perinatal planning.

## Full-text entities

- **Genes:** PAX2 (paired box 2) [NCBI Gene 5076] {aka FSGS7, PAPRS, PAX-2}, MYCN (MYCN proto-oncogene, bHLH transcription factor) [NCBI Gene 4613] {aka FGLDS1, MODED, MPAPA, MYCNsORF, MYCNsPEP, N-myc}, AZIN2 (antizyme inhibitor 2) [NCBI Gene 113451] {aka ADC, AZIB1, ODC-p, ODC1L, ODCp}, HNF1B (HNF1 homeobox B) [NCBI Gene 6928] {aka ADTKD3, FJHN, HNF-1-beta, HNF-1B, HNF1beta, HNF2}
- **Diseases:** Atresia (MESH:D018633), Duodenal atresia (MESH:C535720), familial adenomatous polyposis (MESH:D011125), Choledochal cysts (MESH:D015529), McKusick-Kaufman (MESH:C538159), stones (MESH:D007669), Cloacal malformation (MESH:C564254), intestinal volvulus (MESH:D045822), duplications of the bladder or uterus (MESH:D001745), Abdominal cystic lesions (MESH:C535553), bleeding (MESH:D006470), trauma (MESH:D014947), agenesis (MESH:C536482), Renal lesions (MESH:D007674), skeletal malformations (MESH:C535850), trisomy 21 (MESH:D004314), Multicystic dysplastic kidney (MESH:D021782), enteric cysts (MESH:D004751), torsion (MESH:D050723), Cystic lymphatic malformations (MESH:D008209), dystocia (MESH:D004420), multi-septated gallbladder (MESH:D005705), malformations of the cervix (MESH:D002577), meconium pseudocysts (MESH:D010192), urinary collecting system dilation (MESH:C531743), intraspinal lipomas (MESH:D008067), abscesses (MESH:D000038), cardiac, gastrointestinal (MESH:D005767), Hepatic mesenchymal hamartoma (MESH:D006222), hypoplastic lungs (MESH:D008171), gastroschisis (MESH:D020139), cystic hepatoblastoma (MESH:D018197), patent urachus (MESH:C536474), heart failure (MESH:D006333), lymphatic cysts (MESH:D008210), VACTERL (MESH:C536495), embryonal carcinoma (MESH:D018236), ureterocele (MESH:D014518), Teratomas (MESH:D013724), pelvic anomalies (MESH:D034161), vascular malformation (MESH:D054079), Sacral agenesis (MESH:C537221), Cystic adrenal neuroblastoma (MESH:D009447), Jejunal (MESH:D007579), renal, and vertebral abnormalities (MESH:C538664), meconium ileus (MESH:D000074270), Bronchopulmonary sequestration (MESH:D001998), congenital heart defects (MESH:D006330), Urachal cysts (MESH:D014496), necrotic (MESH:D009336), Polyhydramnios (MESH:D006831), diabetes (MESH:D003920), ischemia (MESH:D007511), ovarian torsion (MESH:D000082843), cloaca (MESH:C537748), vascular injury (MESH:D057772), Ovarian cyst (MESH:D010048), bicornuate or didelphys uterus (MESH:D000093663), aneuploidy (MESH:D000782), vagina (MESH:D014625)
- **Chemicals:** MIBG (MESH:D019797), Gd (MESH:D005682), Hydromucometrocolpos (-), T1 (MESH:C103828)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

13 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12852553/full.md

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Source: https://tomesphere.com/paper/PMC12852553