# Bayesian Mixed Models Approach to Exploring Resilience: Impact of Stress on Subjective Health and Affects Over Time During the COVID‐19 Pandemic

**Authors:** Markus Schepers, Irene Schmidtmann, Sarah K. Schäfer, Simge Yilmaz, Rieke Baumkötter, Alica Hartmann, Julia Petersen, Nora Hettich‐Damm, Philipp Wild, Daniela Zahn, Daniel Wollschläger

PMC · DOI: 10.1002/mpr.70050 · 2026-01-28

## TL;DR

This study uses Bayesian mixed models to explore how stress during the pandemic affects health and emotions over time, finding that social stressors have a stronger negative impact.

## Contribution

The paper introduces a Bayesian mixed models approach for analyzing resilience with ordinal health and affect variables in a longitudinal pandemic context.

## Key findings

- Social stressors like loss of social contacts had stronger negative associations with health and emotions than work-related stress.
- Subjective health and emotions declined during lockdowns but recovered quickly afterward.
- The study emphasizes the importance of social stress in resilience and suggests protective factors like social support for further research.

## Abstract

Profound stressors such as the COVID‐19 pandemic have highlighted the importance of understanding resilience mechanisms and approaches for quantifying them in longitudinal studies.

We used Bayesian mixed models to analyze resilience dynamics with ordinal dependent variables: subjective physical and mental health, and fear, sadness, and anger. The models included fixed effects for individual stressors and random intercepts for participants, applied to the Gutenberg‐COVID‐19 cohort study.

There were 206,912 responses from 7386 participants (mean age 55.09 years, 51.52% women) over one year (Oct 29, 2020 ‐ Oct 25, 2021). Social stressors, such as loss of social contacts, had stronger negative associations with health and negative affects than work‐related stress. Subjective health and emotions declined during lockdowns but quickly recovered afterward.

Our longitudinal study design and mixed‐model analysis highlight the role of social stress and encourage further research into protective factors like social support and positive reappraisal.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096)

## Full-text entities

- **Genes:** FASTK (Fas activated serine/threonine kinase) [NCBI Gene 10922] {aka FAST}
- **Diseases:** stress (MESH:D000079225), anxiety (MESH:D001007), death (MESH:D003643), COVID (MESH:D000086382)
- **Species:** Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049], Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12852500/full.md

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Source: https://tomesphere.com/paper/PMC12852500