# Reversing Anticoagulants: Influence of Anticoagulation Stewardship and Key Considerations for Optimizing Outcomes

**Authors:** William E. Dager, Megan A. Rech, Brian W. Gilbert

PMC · DOI: 10.1177/10600280251356019 · 2025-08-03

## TL;DR

This paper discusses how pharmacist-led anticoagulation stewardship improves outcomes when reversing anticoagulants during urgent bleeding events.

## Contribution

It highlights the role of pharmacists in standardizing and optimizing anticoagulant reversal through stewardship activities.

## Key findings

- Pharmacists' stewardship activities positively influence urgent anticoagulation reversal outcomes.
- Standardized approaches improve management of life-threatening bleeding events.
- Anticoagulation stewardship offers opportunities for better patient care and safety.

## Abstract

The reversal of anticoagulants can be a complex process with limited data describing the optimal overall approach beyond a specific reversal agent. Recent advances in anticoagulation stewardship have created opportunities to standardize and optimize the reversal of anticoagulants, especially in urgent life-threatening bleeding events. This article explores how pharmacists provided anticoagulation stewardship activities positively impact outcomes related to urgent anticoagulation reversal.

## Full-text entities

- **Diseases:** bleeding (MESH:D006470)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12852482/full.md

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Source: https://tomesphere.com/paper/PMC12852482