# Transcatheter closure of paravalvular leak after Bentall surgery in a Marfan patient: a rare case report

**Authors:** Shichao Guo, Zhiyuan Wang, Ning Zhang, Yanbo Dong, Huijun Zhang, Youwei Zhao

PMC · DOI: 10.3389/fcvm.2025.1734565 · 2026-01-15

## TL;DR

A rare case of paravalvular leak after heart surgery in a Marfan patient was successfully treated with a transcatheter closure.

## Contribution

This case report presents a rare and successful transcatheter treatment of paravalvular leak in a Marfan patient post-Bentall surgery.

## Key findings

- A 38-year-old Marfan patient developed a paravalvular leak three months after Bentall surgery.
- Transcatheter closure using a symmetric VSD occluder resolved the leak and improved heart failure symptoms.
- Post-procedural imaging showed near-complete leak resolution and reduced pseudoaneurysm size.

## Abstract

Paravalvular leak (PVL) following Bentall surgery in patients with Marfan syndrome is exceedingly rare. A 38-year-old Marfan patient underwent Bentall + Sun's procedure for Stanford type A aortic dissection with severe aortic regurgitation. On the third month after surgery, the patient was readmitted due to exertional dyspnea. Echocardiography revealed a paravalvular leak with significant left-to-right shunting, leading to symptoms including exertional dyspnea, hepatomegaly, and heart failure. After adequate preparation, the leak was successfully closed using a symmetric VSD occluder. Post-procedural imaging showed near-complete resolution of the leak, significant reduction in the pseudoaneurysm size, and improvement in heart failure symptoms. The patient was discharged in stable condition.

## Linked entities

- **Diseases:** Marfan syndrome (MONDO:0007947), heart failure (MONDO:0005252)

## Full-text entities

- **Diseases:** aortic regurgitation (MESH:D001022), Marfan (MESH:D008382), dyspnea (MESH:D004417), Stanford type A aortic dissection (MESH:D000784), heart failure (MESH:D006333), PVL (MESH:D019559), hepatomegaly (MESH:D006529), pseudoaneurysm (MESH:D017541)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12852474/full.md

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Source: https://tomesphere.com/paper/PMC12852474