# Cavernous hemangioma originating from the cervical vagus nerve masquerading as a schwannoma: a case report

**Authors:** Yiyang Lu, Guochen Zhu, Jianxin Hu, Hui Lv, Yan Xiao

PMC · DOI: 10.3389/fsurg.2025.1703168 · 2026-01-15

## TL;DR

A rare case of a cavernous hemangioma from the cervical vagus nerve was mistaken for a tumor but successfully treated with surgery.

## Contribution

This case report adds a rare instance of peripheral nerve cavernous hemangioma originating from the vagus nerve, expanding diagnostic awareness.

## Key findings

- The lesion was successfully surgically removed with no postoperative complications or neurological deficits.
- Histopathological analysis confirmed the diagnosis of cavernous hemangioma.
- The patient showed no recurrence after 28 months of follow-up.

## Abstract

Peripheral nerve cavernous hemangioma refers to cavernous vascular malformations occurring on peripheral nerves outside the cranial and spinal nerves. It is a rare non-neoplastic condition. We report a case of a 53-year-old female patient who presented with a painless mass in the right mid-lower neck and a foreign body sensation in the pharynx for five months. Preoperative ultrasonography (US), computed tomography (CT), and magnetic resonance imaging (MRI) revealed a well-delineated lesion with minimal blood flow signals, heterogeneous enhancement on contrast-enhanced CT and T1-weighted imaging, and high signal intensity on T2-weighted imaging. The patient underwent complete surgical excision of the lesion. Intraoperatively, the lesion was found to be located between the epineurium and perineurium of the vagus nerve and was completely enucleated. Postoperative histopathological and immunohistochemical analyses confirmed the diagnosis of cavernous hemangioma. The patient recovered without complications and exhibited no hoarseness or other neurological deficits postoperatively. No signs of lesion recurrence were observed during a 28-month follow-up. This case suggests that when managing tumors of the cervical vagus nerve, vascular lesions should be included in the differential diagnosis, although such instances are relatively rare.

## Linked entities

- **Diseases:** cavernous hemangioma (MONDO:0003155), schwannoma (MONDO:0002546)

## Full-text entities

- **Diseases:** cavernous vascular malformations (MESH:D054079), neurological deficits (MESH:D009461), vascular lesions (MESH:D014652), schwannoma (MESH:D009442), Cavernous hemangioma (MESH:D006392), hoarseness (MESH:D006685), tumors (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12852428/full.md

---
Source: https://tomesphere.com/paper/PMC12852428