# Recent Progressions in Applications of Bioactive Polysaccharides in Food and Health Sciences: A Comprehensive Review

**Authors:** M V N L Chaitanya, Bahjat Alhasso, Wadhah Hasan Alkhazali, Ashok Kumar Bishoyi, Rami Oweis, S. Renuka Jyothi, Rishiv Kalia, Laxmidhar Maharana, Ashish Singh Chauhan, Hayder Naji Sameer, Ahmed Yaseen, Zainab H. Athab, Mohaned Adil, Asghar Narmani, Bagher Farhood

PMC · DOI: 10.1002/fsn3.71482 · 2026-01-28

## TL;DR

This review explores how bioactive polysaccharides can improve food safety and health outcomes by preventing diseases and supporting gut health.

## Contribution

The paper provides a comprehensive overview of the diverse applications of polysaccharides in food and health sciences.

## Key findings

- Polysaccharides help ameliorate fatigue and preserve gut microflora.
- They are used in drug delivery systems and regenerative medicine.
- They exhibit anti-inflammatory, antimicrobial, and antioxidant properties.

## Abstract

Nowadays, the incidence and mortality rates of diseases remain major challenges throughout the world. To stop these health‐threatening concerns, a safe diet plays a pivotal role. Polysaccharides, as natural biopolymers, possess remarkable potential in the development of safe and healthy foods to prevent the incidence of diseases and guarantee health. These abundant biopolymers have a high rate of practicality in the food industry and biomedical sciences. Polysaccharides can be found in various living organisms (including plants, seaweeds, animals, and microorganisms) and extracted by a number of advanced techniques. The anti‐inflammatory, immunomodulatory, hypoglycemic, hypocholesterolemic, anticoagulant, antiviral, antimicrobial, and antioxidant activities of polysaccharides have considerable features in the food and health sciences. The applications of polysaccharides in food sciences are mainly owing to ameliorating fatigue, preserving the microflora of the gastrointestinal tract, and providing health for the gut in living organisms. Moreover, polysaccharides have practical applications in pharmaceutical (drug delivery systems) and biomedical (regenerative medicine) sciences, which pave the way for the treatment of diseases. This comprehensive review highlights the potential applications of polysaccharides in food and health sciences.

Polysaccharides play a pivotal role in the development of safe and healthy foods. They ameliorate fatigue, preserve the microflora of the gastrointestinal tract, and provide health for the gut in living organisms. These biopolymers are applied for the fabrication of breakthrough drug delivery systems and potential platforms in regenerative medicine.

## Full-text entities

- **Diseases:** inflammatory (MESH:D007249), fatigue (MESH:D005221)
- **Chemicals:** Polysaccharides (MESH:D011134)

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12852063/full.md

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Source: https://tomesphere.com/paper/PMC12852063