# A Rare Case of Nasal Chondromesenchymal Hamartoma Presenting With Respiratory Distress in a Newborn: A Case Report

**Authors:** Mikiyas Olani, Mohammed Juhar, Siraw Girum, Amanuel Damie, Alemwork Amare, Abel Daniel

PMC · DOI: 10.1155/crot/1090975 · Case Reports in Otolaryngology · 2026-01-28

## TL;DR

A rare nasal tumor in a newborn was successfully treated with surgery, highlighting the importance of accurate diagnosis in infants.

## Contribution

This case report adds to the limited literature on nasal chondromesenchymal hamartoma in neonates and emphasizes diagnostic approaches in resource-limited settings.

## Key findings

- A 4-day-old neonate with a nasal mass was diagnosed with nasal chondromesenchymal hamartoma.
- Endoscopic excision led to complete tumor removal and successful management.
- Proper diagnosis required imaging, histopathology, and molecular tests in a resource-limited setup.

## Abstract

Nasal chondromesenchymal hamartoma (NCMH) is a rare cause of nasal mass in infants and children. It was first described in 1998, and since then, only 63 previous cases have been reported.

Here, we report a case of a 4‐day‐old neonate with a right‐sided nasal mass presenting with respiratory distress since birth. MRI was suggestive of chondromesenchymal hamartoma, for which endoscopic excision was done with complete removal of the tumor. The patient was diagnosed and successfully managed in our setup.

NCMH is a rare cause of nasal obstruction in neonates, with a similar clinical presentation to other known nasal masses. Physical examination, imaging, histopathology, and molecular tests are combined to diagnose such cases. The curative management currently recommended is surgery.

It is always prudent to consider all possible differentials in neonates presenting with a nasal mass. Our report focuses on the role of proper examination, imaging techniques, and histologic evaluation for proper diagnosis and follow‐up in a resource‐limited setup.

## Full-text entities

- **Diseases:** tumor (MESH:D009369), Respiratory Distress (MESH:D012128), nasal mass (MESH:D009668), nasal obstruction (MESH:D015508), NCMH (MESH:D006222)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12848611/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12848611/full.md

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Source: https://tomesphere.com/paper/PMC12848611