# Impact of contrast agents on organ dosimetry in paediatric diagnostic fluoroscopy: the upper gastrointestinal series

**Authors:** Wyatt W Smither, David Borrego, Kimberly Applegate, Wesley E Bolch, Emily L Marshall

PMC · DOI: 10.1088/1361-6560/ae36e3 · Physics in Medicine and Biology · 2026-01-28

## TL;DR

This study shows that using contrast agents in pediatric X-ray exams can reduce radiation doses to certain organs by up to 50%.

## Contribution

The study quantifies the impact of contrast media on organ doses in pediatric UGI fluoroscopy using Monte Carlo simulations.

## Key findings

- Contrast media reduced organ absorbed doses by up to 50% and detriment-weighted doses by up to 26%.
- Dose reductions were observed in organs like the colon, heart wall, and kidneys.
- The study did not account for automatic brightness control effects, which could increase doses.

## Abstract

Objective. Barium and iodinated contrast media are ubiquitous with upper gastrointestinal (UGI) series examinations performed on paediatric patients. The present study quantifies the impact of contrast media on organ absorbed and detriment-weighted doses for UGI examinations. Approach. A paediatric radiologist and a medical physicist created reference imaging fields for four complete UGI series examinations encompassing the newborn and 1-year-old female for both normal and abnormal disease states. Monte Carlo radiation transport simulations were performed for these four cases, with and without contrast media, using the international commission on radiological protection’s voxel-based reference computational phantoms. Main results. Estimates of detriment-weighted dose and absorbed doses to the colon, heart wall, kidneys, lungs, small intestine wall, spleen, stomach wall, thymus, thyroid, and remainder tissues are reported. For fields with contrast media the organ absorbed doses and detriment-weighted dose decreased by up to 50% and 26%, respectively, with the dose for the complete examination, i.e. not per field, decreasing by up to 26% for organs impacted by the presence of contrast media. Significance. Overall, relative doses were shown to decrease for simulations that included contrast media due to selective absorption of the x-ray beam by the contrast media. This study, however, did not investigate the effects of the automatic brightness control which could result in organ absorbed doses increasing due to compensation by the fluoroscopy machine when contrast media is present in the field.

## Linked entities

- **Chemicals:** Barium (PubChem CID 5355457)

## Full-text entities

- **Diseases:** volvulus (MESH:D045822), malrotation (MESH:C562456), VRCPs (MESH:C000719218), UGI (MESH:D005767)
- **Chemicals:** tromethamine (MESH:D014325), Iohexol (MESH:D007472), Barium contrast media (-), tungsten (MESH:D014414), Barium (MESH:D001464), aluminum (MESH:D000535), iodine (MESH:D007455), Edetate calcium disodium (MESH:D004492), barium sulfate (MESH:D001466)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12848563/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12848563/full.md

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Source: https://tomesphere.com/paper/PMC12848563