# Transformer-based intelligent detection model for early dental caries in panoramic radiographs

**Authors:** Liwei Wang, Zhiyuan Li

PMC · DOI: 10.1038/s41598-025-33391-y · Scientific Reports · 2026-01-23

## TL;DR

This paper introduces a Transformer-based model for detecting early dental caries in panoramic radiographs, outperforming traditional methods and dentists in accuracy and speed.

## Contribution

A novel Transformer-based model with enhanced feature fusion and attention mechanisms for early dental caries detection.

## Key findings

- The model achieved 87.3% mean average precision across all caries stages.
- It showed 81.3% sensitivity for D1 lesions and 84.7% for D2 lesions.
- The system processes images in real-time (70 milliseconds per radiograph).

## Abstract

Early detection of dental caries in panoramic radiographs remains challenging due to subtle radiographic features and complex anatomical structures. This study develops a Transformer-based intelligent detection model specifically optimized for identifying early-stage carious lesions in panoramic dental images. The proposed architecture integrates enhanced multi-scale feature fusion mechanisms, spatially-aware attention optimization, and improved two-dimensional positional encoding to capture global contextual relationships while maintaining fine-grained feature discrimination. A comprehensive dataset comprising 3,856 panoramic radiographs with 12,847 annotated carious lesions across severity grades (D1-D4) was constructed for model development and validation. The model achieved 87.3% mean average precision (mAP) across all caries stages, with notable sensitivity of 81.3% for D1 lesions and 84.7% for D2 lesions, surpassing conventional CNN-based approaches and average dentist performance. The system processes images in real-time (70 milliseconds per radiograph). This research demonstrates the efficacy of domain-adapted Transformer architectures for early dental caries detection and establishes its potential utility as a decision support tool for enhancing diagnostic accuracy and screening efficiency in dental practice.

## Linked entities

- **Diseases:** dental caries (MONDO:0005276)

## Full-text entities

- **Diseases:** apical lesions (MESH:D010485), periodontal disease (MESH:D010510), mineral loss (MESH:D012080), dental lesion (MESH:D009057), MSF (MESH:C538175), D1 (MESH:C563980), lesions (MESH:D009059), NMS (MESH:D009459), Dental caries (MESH:D003731), FEM (MESH:C564835)
- **Chemicals:** AMP (MESH:D000249), FPN (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12848152/full.md

## References

33 references — full list in the complete paper: https://tomesphere.com/paper/PMC12848152/full.md

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Source: https://tomesphere.com/paper/PMC12848152