# Recent Progress in the Detection and Monitoring of Toxin-Producing Cyanoprokaryotes and Their Toxins

**Authors:** Milena Pasheva, Milka Nashar, Diana Ivanova

PMC · DOI: 10.3390/toxics14010086 · Toxics · 2026-01-18

## TL;DR

This paper reviews recent methods for detecting and monitoring harmful cyanobacteria and their toxins in water, emphasizing new technologies and challenges.

## Contribution

The paper provides a comprehensive review of current early detection methods for harmful cyanobacterial blooms and their practical limitations.

## Key findings

- Contemporary strategies for monitoring cyanotoxins include molecular genetics, immunoassays, and machine-learning frameworks.
- There are currently no established acceptable limit values for cyanotoxins in water.
- Rising temperatures and human activities are key drivers of increasing toxic cyanobacterial blooms.

## Abstract

Eutrophication of water bodies and the bloom of toxin-producing cyanoprokaryotes raise health concerns. Various cyanoprokaryotes species, including Microcystis, Raphidiopsis, Nodularia, and Chrysosporum, release toxins into the aquatic environment, which can reach concentrations toxic to humans and animals. Rising temperatures and human activities are primary drivers behind the increasing frequency of toxic cyanobacterial blooms. The Word Health Organization (WHO) has established provisional guideline values for cyanotoxins in drinking water and water used for other purposes in daily human activities, and has published guidance for identifying hazards and managing risks posed by cyanobacteria and their toxins. There are currently no acceptable limit values for cyanotoxins. To address monitoring needs, contemporary strategies now incorporate molecular genetics, immunoassays, biochemical profiling, and emerging machine-learning frameworks. This paper reviews current early detection methods for harmful cyanobacterial blooms, highlighting their practical advantages and drawbacks.

## Linked entities

- **Species:** Microcystis (taxon 1125), Raphidiopsis (taxon 244599), Nodularia (taxon 159191), Chrysosporum (taxon 1650335)

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

102 references — full list in the complete paper: https://tomesphere.com/paper/PMC12846077/full.md

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Source: https://tomesphere.com/paper/PMC12846077