Analysis of Research Progress on the Chemical Constituents and Pharmacological Activities of Er-Shiwei Roudoukou Wan
Kai Hao, Lingxiao Chen, Zongyao Wu, Cizhen Danzeng, Xiaorui Cheng
TL;DR
This paper reviews research on Er-Shiwei Roudoukou Wan, a Tibetan medicine, to summarize its chemical makeup and health benefits for better clinical use.
Contribution
The study provides a systematic and bibliometric analysis of Er-Shiwei Roudoukou Wan's research, highlighting gaps and future directions.
Findings
Research hotspots include pharmacological activities, chemical composition, and methodological advances.
The formula shows efficacy in heart–gallbladder syndrome, 'Ninglong disease,' and gynecological disorders.
Pharmacological effects include cardiovascular protection, anti-inflammatory, anticancer, and neuroprotective properties.
Abstract
Ershiwei Roudoukou Wan, a traditional Tibetan medicine, is known for its sedative and tranquilizing properties. Although considerable progress has been made in characterizing its chemical constituents and pharmacological mechanisms, a comprehensive and systematic evaluation remains limited. This study integrates bibliometric analysis with a systematic literature review to summarize current research trends, clarify the chemical basis, and assess pharmacological evidence, thereby supporting rational clinical use. Publications on Ershiwei Roudoukou Wan and its component herbs were retrieved from the Web of Science database. After screening, 7869 articles were analyzed using CiteSpace to generate knowledge maps. Research hotspots centered on pharmacological activities, chemical composition, and methodological advances. Clinically, the formula has shown efficacy in conditions including…
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Taxonomy
TopicsTraditional Chinese Medicine Analysis · Berberine and alkaloids research · Antioxidants, Aging, Portulaca oleracea