# Electrochemical Synthesis of 3-Selenyl-Chromones via Domino C(sp2)-H Bond Selenylation/Annulation of Enaminones

## TL;DR

This paper presents a new electrochemical method to efficiently synthesize 3-selenylated chromone compounds under mild conditions.

## Contribution

A novel electrosynthesis method for 3-selenylated chromones via a domino C(sp2)-H bond selenylation/annulation process.

## Key findings

- The method operates under mild conditions with good functional group tolerance.
- The reaction is scalable and has a wide substrate scope.
- The reaction likely proceeds via a cation pathway based on preliminary experiments.

## Abstract

Herein, we disclose a highly efficient pathway toward 3-selenylated chromone derivatives via electrosynthesis domino C(sp2)-H bond selenylation/cyclization/deamination of 2-hydroxyaryl enaminones with diselenides. This method showed mild conditions, easy operation, a wide substrate scope, and good functional group tolerance. Furthermore, this electrosynthesis strategy was amenable to scaling up the reaction. Additionally, the preliminary experiments revealed that this reaction probably proceeded via a cation pathway instead of a radical pathway.