# Hawthorn (Crataegus monogyna Jacq.): A Review of Therapeutic Potential and Applications

**Authors:** Jagoda Kępińska-Pacelik, Wioletta Biel

PMC · DOI: 10.3390/molecules31020226 · 2026-01-09

## TL;DR

Hawthorn is a plant with strong antioxidant properties that may help improve heart health and manage chronic diseases, but more research is needed to confirm its benefits.

## Contribution

This study reviews hawthorn's antioxidant properties and evaluates its potential as a functional food ingredient.

## Key findings

- Hawthorn contains polyphenols and flavonoids that contribute to its antioxidant capacity.
- It shows beneficial effects on cardiovascular health, including blood pressure and lipid regulation.
- Hawthorn has anti-inflammatory, antimicrobial, and antidiabetic properties.

## Abstract

Hawthorn (Crataegus monogyna Jacq.) is a medicinal and nutritional plant widely recognized for its rich phytochemical composition and diverse health-promoting properties. The fruit, leaves, and flowers contain significant amounts of polyphenols, flavonoids, flavonols, phenolic acids and dye compounds with antioxidant properties that contribute to its strong antioxidant capacity. Numerous studies have demonstrated hawthorn’s beneficial effects on cardiovascular health, including regulation of blood pressure, lipid metabolism, and cardiac function. Additionally, hawthorn exhibits anti-inflammatory, antimicrobial, hypolipidemic, and antidiabetic properties, supporting its role in the prevention and management of chronic diseases. Its potential as a functional food ingredient and natural health supplement is increasingly recognized. However, further clinical trials and standardization of bioactive components are needed to confirm its efficacy, safety, and optimal dosage. Overall, hawthorn represents a valuable natural resource for promoting human health and well-being through diet and phytotherapy. Therefore, the aim of this study is to present—based on the scientific literature—the antioxidant properties of hawthorn and to assess the possibility of using this plant as a functional ingredient.

## Linked entities

- **Chemicals:** flavonols (PubChem CID 11349)

## Full-text entities

- **Diseases:** inflammatory (MESH:D007249), chronic diseases (MESH:D002908)
- **Chemicals:** polyphenols (MESH:D059808), flavonols (MESH:D044948), lipid (MESH:D008055), flavonoids (MESH:D005419), phenolic acids (MESH:C017616)
- **Species:** Crataegus (hawthorn, genus) [taxon 23159], Crataegus monogyna (species) [taxon 140997], Homo sapiens (human, species) [taxon 9606]

## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12844126/full.md

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Source: https://tomesphere.com/paper/PMC12844126