Procyanidins: Structural Properties, Production Methods, and Modern Applications
Aleksandr Yu. Zakharov, Dmitriy Berillo, Annie Ng, Damir S. Aidarkhanov, Anna V. Tukesheva, Kamila M. Temirkulova, Ainur Tanybayeva, Zulkhair A. Mansurov, Mannix P. Balanay, Vladimir V. Pavlenko
TL;DR
This paper reviews procyanidins, their structures, production methods, and applications in health and materials science.
Contribution
It provides a comprehensive and updated analysis of procyanidin research from 2005 to 2025, emphasizing structural analysis and extraction methods.
Findings
Procyanidins are bioactive compounds with potential in health and material design.
Advanced NMR techniques are crucial for understanding their structural conformation.
Natural and synthetic methods are both explored for their extraction and production.
Abstract
Procyanidins, a class of substances widely distributed in nature, have attracted the attention of the scientific community due to their bioactive properties, especially with regard to human health. This review is based on an extensive examination of peer-reviewed literature, patents, and clinical trial reports published between 2005 and 2025. From an initial pool of more than 300 documents, 283 studies were selected according to criteria of scientific rigor, methodological clarity, and relevance to the research objectives. A literature search was performed using PubMed, PubChem, Google Scholar, Scopus and ResearchGate employing keywords such as Procyanidins, chemical structure, extraction, and health effects. This article provides a comprehensive overview of current methods for obtaining these compounds, which include both natural sources and synthetic approaches. It provides a concise…
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Taxonomy
TopicsFree Radicals and Antioxidants · Computational Drug Discovery Methods · Molecular spectroscopy and chirality