# The Prevalence of Medically Unexplained Symptoms in Emergency Neurology Service

**Authors:** Marija Ernoić, Lana Oštro, Petra Črnac, Jelena Košćak Lukač, Marina Milošević, Latica Friedrich, Josip Sremec, Ana Sruk, Berislav Dalić, Ivan Bielen, Sanja Tomasović, Darija Mahović, Hrvoje Budinčević

PMC · DOI: 10.3390/medicina62010121 · Medicina · 2026-01-06

## TL;DR

This study found that about 10% of patients in an emergency neurology service had symptoms that could not be fully explained by known medical conditions.

## Contribution

The study quantifies the prevalence of medically unexplained symptoms in an emergency neurology setting.

## Key findings

- 2.7% of patients had symptoms not at all explained by organic disease.
- Approximately 10% of patients had symptoms poorly explained by identifiable organic disease.

## Abstract

Background and Objectives: Medically unexplained symptoms (MUS) represent a clinical syndrome encompassing conditions in which patients present with symptoms that cannot be adequately explained by identifiable organic pathology or do not meet established diagnostic criteria for organic disease. These symptoms pose a diagnostic and management challenge, particularly in acute care settings. The objective of this study was to determine the proportion of patients presenting with MUS to the Emergency Neurology Service of a tertiary care hospital. Materials and Methods: This retrospective study was conducted at the Emergency Neurology Service of Sveti Duh University Hospital. All patients who were triaged for neurological examination during the study period were included. Following clinical evaluation, attending neurologists assessed the extent to which each patient’s symptoms could be explained by organic disease (“organicity”). This assessment was recorded using a Likert scale ranging from “not at all explained” to “completely explained. Results: Out of 219 patients, 2.7% had symptoms that were rated as “not at all explained” by organic disease, 7.3% “somewhat explained”, 23.3% “largely explained” and 66.7% “completely explained” by organic disease. Conclusions: Approximately one-tenth of patients presenting to our Emergency Neurology Service have symptoms that are poorly explained by identifiable organic disease.

## Full-text entities

- **Diseases:** organic disease (MESH:D000092124), MUS (MESH:D000071896)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12843267/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12843267/full.md

## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12843267/full.md

---
Source: https://tomesphere.com/paper/PMC12843267