# Prosthetic Joint Infections in Trapeziometacarpal Arthroplasty: A Comprehensive Systematic Review

**Authors:** Guido Bocchino, Silvia Pietramala, Stella La Rocca, Giulia Di Pietro, Alessandro El Motassime, Giacomo Capece, Domenico De Mauro, Camillo Fulchignoni, Giulio Maccauro, Raffaele Vitiello

PMC · DOI: 10.3390/jpm16010035 · Journal of Personalized Medicine · 2026-01-05

## TL;DR

This paper reviews prosthetic joint infections in TMC arthroplasty, finding them rare but challenging to manage due to inconsistent reporting and treatment.

## Contribution

The study provides a systematic review of infection rates and management in TMC joint prostheses, highlighting the need for standardized protocols.

## Key findings

- Only 0.36% of 4165 TMC joint procedures had infections, with Staphylococcus aureus in two cases.
- Infection management included antibiotics, debridement, and prosthesis removal with or without reimplantation.
- Inconsistent diagnostic criteria and treatment approaches limit uniform conclusions.

## Abstract

Background: Osteoarthritisof the first trapeziometacarpal (TMC) joint (rhizarthrosis) is a degenerative condition causing pain, reduced mobility, and functional limitations, particularly in older adults and postmenopausal women. Though conservative treatments offer symptomatic relief, advanced cases often require trapeziectomy or total joint replacement. The choice of prosthesis is tailored to patient-specific factors such as age, functional demands, and comorbidities. Despite the benefits of TMC joint replacements, prosthetic infections remain underexplored. Materials and Methods: This systematic review (covering 2000–2024) adhered to PRISMA guidelines, searching Medline, Cochrane, and Google Scholar for randomized controlled trials and case series. Data on demographics, prosthesis types, infection rates, and management strategies were extracted and analyzed. Results: Among 4165 TMC joint procedures reported in 63 studies, 15 cases (0.36%) involved superficial or deep infections, with Staphylococcus aureus identified in two instances. Management ranged from antibiotic therapy and debridement to prosthesis removal with or without reimplantation. Conclusions: Variability in diagnostic criteria and reporting limited uniform conclusions. Although infections are infrequent, they pose significant management challenges due to inconsistent diagnostic criteria and treatments. Early identification and tailored interventions remain critical. This review underscores the need for standardized protocols and highlights gaps in current research. Future studies should focus on multicenter trials and robust methodologies to improve outcomes and advance infection management in TMC prosthesis surgery.

## Linked entities

- **Diseases:** osteoarthritis (MONDO:0005178)

## Full-text entities

- **Diseases:** Infections (MESH:D007239), degenerative condition (MESH:D019636), pain (MESH:D010146)
- **Species:** Staphylococcus aureus (species) [taxon 1280], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12843138/full.md

## References

78 references — full list in the complete paper: https://tomesphere.com/paper/PMC12843138/full.md

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Source: https://tomesphere.com/paper/PMC12843138