# Establishing a Robot-Assisted Liver Surgery Program: Early Experience from University Medical Center Ljubljana

**Authors:** Miha Petrič, Živa Nardin, Jan Grosek, Aleš Tomažič, Boštjan Plešnik, Blaž Trotovšek

PMC · DOI: 10.3390/medicina62010018 · Medicina · 2025-12-22

## TL;DR

This paper shares early experiences of using robots for liver surgery at a medical center, showing it can be safe and effective with proper training and planning.

## Contribution

The paper provides a detailed account of implementing robotic liver surgery in a new setting with specific outcomes and recommendations.

## Key findings

- Median operative duration was 166 minutes with low blood loss and transfusion rates.
- R0 resection rate for malignant tumors was 88.2%, indicating effective tumor removal.
- Postoperative complications were observed in 10% of patients, with no mortality within 90 days.

## Abstract

Background and Objectives: Robot-assisted procedures represent a significant advancement in minimally invasive liver resection techniques. Nonetheless, the introduction of a novel surgical technique in a new environment necessitates meticulous planning and a gradual, stepwise approach. This study describes the adoption of a robotic surgical platform for liver resection at a high-volume tertiary care center. Materials and Methods: We retrospectively analyzed data that had been prospectively collected from fifty robot-assisted liver resections. Descriptive statistics, including frequencies, percentages, means/medians, and standard deviations, were employed for description and summary. Results: The median operative duration was 166 min (range: 85–400 min), with an average intraoperative blood loss of 200 mL (range: 50–1000 milliliters). Intraoperative or postoperative blood transfusion was required in 8% of patients. Conversion to open resection was necessary in one patient (2%). The mean duration of hospitalization was 5 days (range: 3–20 days), with a 30-day readmission rate of 6% and no mortality within 90 days. Postoperative complications classified as Clavien-Dindo grade 3 or higher were observed in five patients (10%). The mean tumor size varied according to pathology: 58.5 mm (range: 30–120 mm) in the hepatocellular carcinoma group; 27.4 mm (range: 10–32 mm) in the secondary malignancy group; and 42.6 mm (range: 24–60 mm) in the intrahepatic cholangiocarcinoma group. The median number of lymph nodes harvested during lymphadenectomy (IHHCA/GBCA) was 5.4, ranging from 1 to 11. The R0 resection rate for malignant tumors was 88.2% (of 30/34). Conclusions: This study validates the safe integration of robot-assisted surgery into liver disease treatment, supported by our initial experience. Despite its technical advantages, robotic-assisted liver surgery remains complex and demanding. Structured robotic training within established programs, meticulous patient selection, and a stepwise implementation approach are critical during the early phases to optimize the outcomes.

## Linked entities

- **Diseases:** hepatocellular carcinoma (MONDO:0007256), secondary malignancy (MONDO:0024881), intrahepatic cholangiocarcinoma (MONDO:0003210)

## Full-text entities

- **Diseases:** blood (MESH:D006402), malignancy (MESH:D009369), hepatocellular carcinoma (MESH:D006528), liver disease (MESH:D008107), intrahepatic cholangiocarcinoma (MESH:D018281)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

39 references — full list in the complete paper: https://tomesphere.com/paper/PMC12842929/full.md

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Source: https://tomesphere.com/paper/PMC12842929