# Palliative Ventral Hernia Repair Using Onlay Mesh and Antibiotic Beads in High-Risk Patients

**Authors:** Fazal Khan, Stephanie Heller, Erica A. Loomis, Mariela Rivera, Henry Schiller

PMC · DOI: 10.3390/medicina62010074 · Medicina · 2025-12-30

## TL;DR

This study presents a new surgical approach for high-risk patients with ventral hernias using mesh and antibiotic beads, showing acceptable outcomes.

## Contribution

A novel palliative ventral hernia repair pathway using onlay mesh and antibiotic beads for high-risk patients.

## Key findings

- Hernia recurrence occurred in 9.3% of patients with a mean follow-up of 24.1 months.
- Skin separation and seroma formation were the most common wound complications.
- Three patients had mesh rupture and one had recurrence, all successfully repaired.

## Abstract

Background and Objectives: There are many well-described approaches to symptomatic ventral hernia management; however, there remains a significant patient population with limited options for a durable ventral hernia repair with a reasonable risk of infection and recurrence. Drawing from the orthopedic literature, we changed our approach to this clinical problem and developed a palliative ventral hernioplasty pathway. Materials and Methods: A retrospective review (2017–2019) of patients’ palliative ventral hernioplasty was performed. Results: In total, 43 patients included, with a female preponderance of 24 (58.6%) and a mean age 61.5 ± 11.5 years. The mean BMI was 38.1 kg/m2 (IQR: 25.4–62), and 28 patients (65.1%) had a history of prior wound/mesh infection. Urgent repair was performed in 14 patients. Overall polypropylene prosthetic was implanted in 26 patients, and bioprosthetic/absorbable mesh was used in the remaining. The mean surface area of the implanted mesh was 561 cm2. The most common wound complications identified were skin separation (30.2%) and seroma formation (48.8%). Hernia recurrence occurred in four (9.3%) patients, with a mean follow-up of 24.1 months (9–37). Three patients had central lightweight mesh rupture and one had a recurrence (bioprosthetic mesh); all were subsequently repaired. Conclusions: Despite the small number of patients, our palliative ventral hernia repair pathway offers durable repair with an acceptable risk of recurrence and mesh infection in patients who would otherwise be considered nonoperative.

## Full-text entities

- **Diseases:** seroma (MESH:D049291), Hernia (MESH:D006547), Ventral Hernia (MESH:D006555), infection (MESH:D007239), rupture (MESH:D012421)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12842800/full.md

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Source: https://tomesphere.com/paper/PMC12842800