# Retroauricular Kimura Disease in a Young European Female: A Rare Case and Review of the Literature

## TL;DR

A rare case of Kimura disease in a young European woman is reported, highlighting its unusual presentation outside typical endemic regions.

## Contribution

This is a rare report of Kimura disease in a non-Asian female, expanding understanding of its variable clinical presentation.

## Key findings

- The patient presented with a retroauricular mass, peripheral eosinophilia, and elevated IgE, consistent with KD.
- Histopathology confirmed features of KD, including eosinophilic microabscesses and lymphoid follicular hyperplasia.
- Exclusion of angiolymphoid hyperplasia with eosinophilia confirmed the diagnosis of Kimura disease.

## Abstract

Background: Kimura disease (KD) is a rare benign disorder usually presenting in young Asian males as a subcutaneous mass in the head and neck. Common histological findings include lymphoid follicular hyperplasia, eosinophilic infiltrates, and vascular proliferation. Non-endemic presentations, particularly in women, are rare. Methods: We report a case of isolated retroauricular KD in a 28-year-old White woman with a 3-year history of an isolated, enlarging, mildly painful retroauricular mass, accompanied by peripheral eosinophilia and elevated serum immunoglobulin E (IgE) levels. The mass was resected, imaging showed no other sites of concern, and there was no recurrence. Results: Histopathologically, eosinophilic microabscesses, prominent vascular proliferation, and lymphoid follicular hyperplasia with CD20+ B cells, CD3+ T cells, and preserved CD23+ follicular dendritic networks were identified. Conclusions: A diagnosis of angiolymphoid hyperplasia with eosinophilia (ALHE) was excluded, and a final diagnosis of KD was established.