# Diagnostic Pitfalls of Dental Follicles and Cyst-like Lesions in Juvenile Patients: An Early Odontogenic Myxoma Mimicking a Follicular Cyst

**Authors:** Kamil Nelke, Klaudiusz Łuczak, Michał Gontarz, Grażyna Wyszyńska-Pawelec, Agata Małyszek, Ömer Uranbey, Dayel Gerardo Rosales Díaz Mirón, Maciej Dobrzyński, Małgorzata Tarnowska, Piotr Kuropka

PMC · DOI: 10.3390/jcm15020599 · Journal of Clinical Medicine · 2026-01-12

## TL;DR

This paper discusses how dental follicles and cyst-like lesions in children can be misdiagnosed, highlighting a case where an early odontogenic myxoma was mistaken for a follicular cyst.

## Contribution

The paper presents a case demonstrating how atypical dental follicle appearances on radiographs may indicate early odontogenic myxoma in juveniles.

## Key findings

- Atypical signs on OPGs may suggest odontogenic tumors in juvenile patients.
- Early stages of odontogenic myxoma can mimic follicular cysts on radiographs.
- Histopathological evaluation is crucial for accurate diagnosis and treatment planning.

## Abstract

The occurrence of cysts and tumors in pediatric patients varies across different age groups. Follicular and dentigerous cysts are among the most common lesions. However, typical odontogenic tumors in juvenile patients are not frequently observed. Early stages of cyst and odontogenic tumor development might exhibit some similar characteristics due to the presence of unerupted teeth or their relationship with various stages of tooth formation and eruption. Many small lesions are discovered accidentally on routine orthopantomography (OPG), while the bigger ones manifest themselves as bone swelling, cortical perforation, or displacement and mobility of teeth. Each odontogenic tumor has characteristic clinical and radiological features. Biopsy of larger lesions, or incisional biopsy of smaller lesions, allows detailed histopathological evaluation to determine tumor type and growth behavior and guide appropriate treatment planning. In some cases, atypical signs on OPGs, like asymmetry in dental follicles, occurrence of round or oval bone lesions near impacted or retained teeth, and visibility of irregular radiolucent, radiopaque, or mixed jawbone lesions, might suggest the occurrence of some possible odontogenic tumor in juvenile patients. Each case should be handled individually. In this case, we demonstrate how atypical appearances of dental follicles on panoramic radiographs may not correspond with cone-beam computed tomography findings and may indicate the early stages of odontogenic myxoma in a juvenile patient.

## Full-text entities

- **Diseases:** jawbone lesions (MESH:D009059), odontogenic tumor (MESH:D009808), bone lesions (MESH:D001847), Dental Follicles (MESH:D000072717), unerupted (MESH:D014097), Follicular and dentigerous cysts (MESH:D003803), tumor (MESH:D009369), Cyst (MESH:D003560), Odontogenic Myxoma (MESH:D009232)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12842373/full.md

## References

26 references — full list in the complete paper: https://tomesphere.com/paper/PMC12842373/full.md

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Source: https://tomesphere.com/paper/PMC12842373